From the charming villages of the Tuscan countryside to the medieval city of Dubrovnik, the best way to explore the Mediterranean is sailing from port to port on a luxury cruise. With Crystal Cruises, enjoy exceptional service, unforgettable experiences, and a plethora of included amenities.
Search the sailings below or call our experts at 1 (877) 734-6858 to start planning your future cruise with Crystal.
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| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
| 7-night Mediterranean Cruise Provence (Marseille) to Tarragona | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 5/28/25 | From $5,300 |
| 9-night Mediterranean Cruise Barcelona (Tarragona) to Rome (Civitavecchia) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 6/4/25 | From $6,300 |
| 16-night Europe & Mediterrean Cruise Provence (Marseille) to Portsmouth, UK | Cruise Line Crystal Cruises | Cruise Ship Crystal Serenity | Departs 6/6/25 | From $12,800 |
| 6-night Mediterranean Cruise Provence (Marseille) to Lisbon | Cruise Line Crystal Cruises | Cruise Ship Crystal Serenity | Departs 6/6/25 | From $4,600 |
| 18-night Mediterrean Cruise Rome (Civitavecchia) to Athens (Piraeus) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 6/13/25 | From $13,800 |
| 9-night Amalfi & Adriatic Cruise Rome (Civitavecchia) to Venice | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 6/13/25 | From $7,600 |
| 9-night Adriatic Cruise Venice to Athens (Piraeus) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 6/22/25 | From $6,900 |
| 9-night Mediterranean Cruise Athens (Piraeus) to Thessaloniki | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 7/1/25 | From $6,600 |
| 8-night Mediterranean Cruise Thessaloniki to Rome (Civitavecchia) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 7/10/25 | From $6,300 |
| 5-night Mediterranean Cruise Rome (Civitavecchia) to Monte Carlo | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 7/18/25 | From $4,800 |
| 10-night Mediterranean Cruise Monte Carlo to Athens (Piraeus) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 7/23/25 | From $7,900 |
| 7-night Mediterranean Cruise Roundtrip Athens (Piraeus) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 8/2/25 | From $5,300 |
| 11-night Mediterranean Cruise Roundtrip Athens (Piraeus) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 8/9/25 | From $8,100 |
| 21-night Mediterrean Cruise Athens (Piraeus) to Rome (Civitavecchia) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 8/20/25 | From $15,200 |
| 10-night Adriatic Cruise Athens (Piraeus) to Venice | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 8/20/25 | From $7,300 |
| 26-night Mediterrean Cruise Venice to Barcelona | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 8/30/25 | From $19,900 |
| 11-night Adriatic & Amalfi Cruise Venice to Rome (Civitavecchia) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 8/30/25 | From $8,400 |
| 7-night Mediterranean Cruise Rome (Civitavecchia) to Monte Carlo | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 9/10/25 | From $6,200 |
| 15-night Mediterrean Cruise Rome (Civitavecchia) to Barcelona | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 9/10/25 | From $11,800 |
| 8-night Mediterranean Cruise Monte Carlo to Barcelona | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 9/17/25 | From $6,300 |
| 9-night Mediterranean Cruise Barcelona to Lisbon | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 9/25/25 | From $7,300 |
| 17-night Mediterrean Cruise Roundtrip Barcelona | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 9/25/25 | From $13,700 |
| 8-night Mediterranean Cruise Lisbon to Barcelona | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 10/4/25 | From $5,900 |
| 9-night Mediterranean Cruise Barcelona to Rome (Civitavecchia) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 10/12/25 | From $6,300 |
| 10-night Mediterranean Cruise Rome (Civitavecchia) to Provence (Marseille) | Cruise Line Crystal Cruises | Cruise Ship Crystal Symphony | Departs 10/21/25 | From $6,900 |
| 135-night 2026 World Cruise Los Angeles to Rome (Civitavecchia) | Cruise Line Crystal Cruises | Cruise Ship Crystal Serenity | Departs 1/11/26 | From $84,000 |
Fares/rates are per person, based on double occupancy for select sail and travel dates; are capacity controlled and subject to availability at time booking and may be pulled without notice. We reserve the right to correct errors. Information and pricing is subject to change without notice. While we do our very best to ensure that information and pricing appearing in this website is complete and accurate, we cannot be responsible for incomplete and inaccurate representations, which may or may not be under our control. In the event of a pricing error, misrepresentation or omission, we reserve the right to adjust the pricing or make any other corrections.