Cruise lines sail to worldwide destinations from all over the United States, and whether you fly into a port city or drive there from nearby, each location offers its own charm, culture, climate and cuisine that will round out any cruise vacation. The heart of America beats through an eclectic collection of pulsating metropolises, iconic landscapes, interesting attractions, and off-the-beaten path oases. Whether you're relaxing on a Texas coastline, touring the historic cities of the Southeast, or enjoying the urban landscapes of the Northeast – no matter where your cruise departs from, America is certain to take your breath away.
1,156 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
7-night Canada & New England Cruise: Portland & Bar Harbor
Roundtrip Boston |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Gem
|
Departs
8/29/25
|
From
$1,402
|
|
7-night Cape Codder Cruise
Roundtrip Boston |
Cruise Line
American Cruise Lines
|
Cruise Ship
American Legend
|
Departs
8/29/25
|
Call For Pricing
|
|
7-night Canada & New England: Unesco Sites & Quebecois Nights Cruise
Boston to Quebec |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
8/30/25
|
From
$1,354
|
|
10-night Classic Canada & New England Cruise
Boston to Quebec City |
Cruise Line
Princess Cruises
|
Cruise Ship
Majestic Princess
|
Departs
8/30/25
|
From
$1,758
|
|
8-night Western Caribbean & Perfect Day Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Harmony of the Seas
|
Departs
8/30/25
|
From
$992
|
|
15-night Maple Explorer Cruisetour #2C
Boston to Toronto |
Cruise Line
Princess Cruises
|
Cruise Ship
Majestic Princess
|
Departs
8/30/25
|
From
$4,959
|
|
14-night Grand New England Cruise
Roundtrip Boston |
Cruise Line
American Cruise Lines
|
Cruise Ship
American Patriot
|
Departs
8/30/25
|
Call For Pricing
|
|
14-night Canada & New England: Unesco Sites & Nights Collector Cruise
Roundtrip Boston |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
8/30/25
|
From
$2,613
|
|
5-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Mariner of the Seas
|
Departs
9/1/25
|
From
$570
|
|
7-night Canada & New England Cruise
Boston to Quebec City |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Gem
|
Departs
9/5/25
|
From
$1,209
|
|
7-night Cape Codder Cruise
Roundtrip Boston |
Cruise Line
American Cruise Lines
|
Cruise Ship
American Legend
|
Departs
9/5/25
|
Call For Pricing
|
|
5-night Bermuda Cruise
Roundtrip Baltimore |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Vision of the Seas
|
Departs
9/6/25
|
From
$696
|
|
5-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Mariner of the Seas
|
Departs
9/6/25
|
From
$473
|
|
7-night Canada & New England: Maine, Maritimes & Montreal Cruise
Boston to Montreal |
Cruise Line
Holland America Line
|
Cruise Ship
Volendam
|
Departs
9/7/25
|
From
$1,363
|
|
6-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Harmony of the Seas
|
Departs
9/7/25
|
From
$785
|
|
11-night Canada, Maine & Boston Cruise
Roundtrip Boston |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Silhouette
|
Departs
9/7/25
|
Call For Pricing
|
|
14-night Canada & New England: Maritimes & Montreal Collectors Cruise
Roundtrip Boston |
Cruise Line
Holland America Line
|
Cruise Ship
Volendam
|
Departs
9/7/25
|
From
$2,886
|
|
9-night Canada & New England Cruise
Roundtrip Baltimore |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Vision of the Seas
|
Departs
9/11/25
|
From
$873
|
|
4-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Mariner of the Seas
|
Departs
9/11/25
|
From
$490
|
|
7-night Cape Codder Cruise
Roundtrip Boston |
Cruise Line
American Cruise Lines
|
Cruise Ship
American Legend
|
Departs
9/12/25
|
Call For Pricing
|
|
7-night Canada & New England: Unesco Sites & Quebecois Nights Cruise
Boston to Quebec |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
9/13/25
|
From
$1,258
|
|
8-night Western Caribbean & Perfect Day Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Harmony of the Seas
|
Departs
9/13/25
|
From
$899
|
|
14-night Grand New England Cruise
Roundtrip Boston |
Cruise Line
American Cruise Lines
|
Cruise Ship
American Patriot
|
Departs
9/13/25
|
Call For Pricing
|
|
14-night Canada & New England: Unesco Sites & Nights Collector Cruise
Roundtrip Boston |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
9/13/25
|
From
$2,812
|