Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

4,941 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

Itinerary	Cruise Line	Cruise Ship	Departing	From Price
11-night Quito and Galápagos Inner Loop Cruise/Land Package Roundtrip Quito	Cruise Line Celebrity Cruises	Cruise Ship Celebrity Flora	Departs 4/25/25	$12,048 From $12,048 See Itinerary
16-night Galápagos Inner Loop and Machu Picchu Cruise/Land Package Quito to Lima	Cruise Line Celebrity Cruises	Cruise Ship Celebrity Flora	Departs 4/25/25	$18,608 From $18,608 See Itinerary
10-night Wild Galapagos & Peru Escape Cruise Lima to Guayaquil	Cruise Line Lindblad Expeditions	Cruise Ship National Geographic Islander II	Departs 4/25/25	$11,907 From $11,907 See Itinerary
7-night West Galapagos Expedition Cruise Puerto Ayora to Baltra Island	Cruise Line Aqua Expeditions	Cruise Ship Aqua Mare	Departs 4/25/25	Call For Pricing Call For Pricing See Itinerary
18-night Northwest Passage Expedition Cruise Tokyo to Vancouver	Cruise Line Regent Seven Seas Cruises	Cruise Ship Seven Seas Explorer	Departs 4/26/25	$13,499 From $13,499 See Itinerary
7-night Galapagos Northern Loop Cruise Roundtrip Isla Baltra	Cruise Line Celebrity Cruises	Cruise Ship Celebrity Xpedition	Departs 4/26/25	$7,327 From $7,327 See Itinerary
7-night Wonders of Colombia Cruise Cartagena to Barranquilla	Cruise Line AmaWaterways	Cruise Ship AmaMagdalena	Departs 4/26/25	$3,599 From $3,599 See Itinerary
7-night Mexican Riviera Cruise Roundtrip San Diego	Cruise Line Holland America Line	Cruise Ship Zaandam	Departs 4/26/25	$746 From $746 See Itinerary
11-night Mexican Riviera & Pacific Coast Cruise San Diego to Vancouver, BC	Cruise Line Holland America Line	Cruise Ship Zaandam	Departs 4/26/25	$1,459 From $1,459 See Itinerary
14-night Caribbean East/West Adventurer Cruise Roundtrip Ft. Lauderdale	Cruise Line Princess Cruises	Cruise Ship Enchanted Princess	Departs 4/26/25	Call For Pricing Call For Pricing See Itinerary
7-night Galapagos Southern Loop Cruise Roundtrip Isla Baltra	Cruise Line Celebrity Cruises	Cruise Ship Celebrity Xploration	Departs 4/26/25	$5,907 From $5,907 See Itinerary
10-night Wonders of Colombia with 3 nights in Panama City Cruise/Land Package Cartagena to Barranquilla	Cruise Line AmaWaterways	Cruise Ship AmaMagdalena	Departs 4/26/25	Call For Pricing Call For Pricing See Itinerary
7-night Galápagos Islands Cruise Roundtrip Isla San Cristobal (Puerto Baquerizo Moreno)	Cruise Line Silversea Cruises	Cruise Ship Silver Origin	Departs 4/26/25	$14,000 From $14,000 See Itinerary
7-night Eastern Caribbean Cruise Roundtrip Port Canaveral	Cruise Line Norwegian Cruise Line	Cruise Ship Norwegian New Build	Departs 4/26/25	Call For Pricing Call For Pricing See Itinerary
7-night Galapagos Inner Loop Cruise Roundtrip Isla Baltra	Cruise Line Celebrity Cruises	Cruise Ship Celebrity Flora	Departs 4/27/25	$9,928 From $9,928 See Itinerary
15-night North Pacific Crossing Cruise Yokohama (Tokyo) to Vancouver	Cruise Line Holland America Line	Cruise Ship Noordam	Departs 4/27/25	$1,466 From $1,466 See Itinerary
20-night Pacific Passage: Golden Week To Glacier Bay Cruise Yokohama (Tokyo) to Vancouver	Cruise Line Seabourn	Cruise Ship Seabourn Quest	Departs 4/27/25	$8,969 From $8,969 See Itinerary
7-night Eastern Caribbean Cruise Roundtrip Miami	Cruise Line Norwegian Cruise Line	Cruise Ship Norwegian Escape	Departs 4/27/25	$698 From $698 See Itinerary
4-night Catalina & Ensenada Cruise Roundtrip Los Angeles	Cruise Line Royal Caribbean International	Cruise Ship Navigator of the Seas	Departs 4/28/25	$315 From $315 See Itinerary
6-night Puerto Plata, Labadee, Perfect Day Cruise Roundtrip Ft. Lauderdale	Cruise Line Celebrity Cruises	Cruise Ship Celebrity Beyond	Departs 4/28/25	$1,332 From $1,332 See Itinerary
6-night Wild Galapagos Escape Cruise Roundtrip Guayaquil	Cruise Line Lindblad Expeditions	Cruise Ship National Geographic Islander II	Departs 4/29/25	$9,578 From $9,578 See Itinerary
13-night Hawaii & British Columbia Cruise Honolulu (Oahu) to Vancouver	Cruise Line Princess Cruises	Cruise Ship Royal Princess	Departs 4/30/25	Call For Pricing Call For Pricing See Itinerary
10-night Magic of Colombia with 3 nights Medellin Cruise/Land Package Barranquilla to Cartagena	Cruise Line AmaWaterways	Cruise Ship AmaMagdalena	Departs 4/30/25	$4,774 From $4,774 See Itinerary
7-night Magic of Colombia with 3 nights Medellin Pre-Cruise and 3 Nights Panama City Post-Cruise Cruise/Land Package Medellin to Panama City	Cruise Line AmaWaterways	Cruise Ship AmaMagdalena	Departs 4/30/25	Call For Pricing Call For Pricing See Itinerary

« Previous Next »

Search cruises

Central & South America

Central & South America Cruises