Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
4,999 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
---|---|---|---|---|
11-night Quito and Galápagos Outer Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
4/18/25
|
From
$11,208
|
7-night East Galapagos Expedition Cruise
Baltra Island to Puerto Ayora |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
4/18/25
|
Call For Pricing
|
14-night East & West Galapagos Expedition Cruise
Roundtrip Baltra Island |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
4/18/25
|
Call For Pricing
|
7-night Galapagos Southern Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
4/19/25
|
From
$6,195
|
7-night Galapagos Northern Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
4/19/25
|
From
$6,307
|
7-night Magic of Colombia Cruise
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
4/19/25
|
From
$3,599
|
7-night Classic California Coast Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/19/25
|
From
$746
|
7-night Eastern Caribbean With Puerto Rico Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Princess Cruises
|
Cruise Ship
Enchanted Princess
|
Departs
4/19/25
|
From
$799
|
14-night Caribbean East/West Adventurer Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Princess Cruises
|
Cruise Ship
Enchanted Princess
|
Departs
4/19/25
|
Call For Pricing
|
14-night Mexican Riviera & Classic California Coast Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/19/25
|
From
$1,919
|
7-night Mexican Riviera Cruise
Roundtrip Los Angeles |
Cruise Line
Princess Cruises
|
Cruise Ship
Discovery Princess
|
Departs
4/19/25
|
Call For Pricing
|
10-night Magic of Colombia with 3 Nights Panama Cruise/Land Package
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
4/19/25
|
Call For Pricing
|
7-night Galápagos Islands Cruise
Roundtrip Isla San Cristobal (Puerto Baquerizo Moreno) |
Cruise Line
Silversea Cruises
|
Cruise Ship
Silver Origin
|
Departs
4/19/25
|
From
$13,700
|
15-night Panama Canal Cruise
Tampa to Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Radiance of the Seas
|
Departs
4/19/25
|
From
$1,262
|
7-night Wild Galapagos Escape Cruise
Roundtrip Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
4/19/25
|
From
$11,478
|
15-night Hidden Galápagos and Peru Cruise/Land Package
Lima to Guayaquil |
Cruise Line
Tauck Cruises
|
Cruise Ship
Silver Origin for Tauck
|
Departs
4/19/25
|
Call For Pricing
|
3-night Amazon Discovery Cruise
Iquitos to Nauta |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
4/19/25
|
Call For Pricing
|
7-night Amazon Expeditions Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
4/19/25
|
Call For Pricing
|
18-night Tahitian Treasures Cruise
Sydney to Oahu |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Edge
|
Departs
4/20/25
|
From
$3,564
|
7-night Galapagos Outer Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
4/20/25
|
From
$9,088
|
7-night Classic California Coast Cruise
Roundtrip San Francisco |
Cruise Line
Princess Cruises
|
Cruise Ship
Ruby Princess
|
Departs
4/20/25
|
Call For Pricing
|
11-night Grand Caribbean Cruise
New Orleans to New York City |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Getaway
|
Departs
4/20/25
|
From
$1,199
|
14-night Discover the Galápagos and Peru Cruise/Land Package
Lima to Quito |
Cruise Line
Avalon Waterways
|
Cruise Ship
Treasure of Galápagos
|
Departs
4/20/25
|
From
$9,973
|
19-night Discover the Galápagos and Peru with the Amazon Cruise/Land Package
Lima to Quito |
Cruise Line
Avalon Waterways
|
Cruise Ship
Treasure of Galápagos
|
Departs
4/20/25
|
From
$12,550
|