Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

5,531 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

14-night Panama Canal Cruise

San Diego to Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Zaandam
Departs
4/4/23
4-night Amazon River Expedition Cruise - High Water Season

Nauta to Iquitos

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
4/4/23
 
Call For Pricing
32-night Hawaii, Tahiti, and South Pacific Crossing Cruise

Sydney to Vancouver

Cruise Line
Princess Cruises
Cruise Ship
Majestic Princess
Departs
4/4/23
From
$5,573
10-night Galápagos Islands Expedition Cruise – Nine of the Best Isles

Quito to Guayaquil

Cruise Line
Hurtigruten
Cruise Ship
MS Santa Cruz
Departs
4/4/23
From
$10,420
6-night Galápagos Islands Expedition Cruise – Iconic Wildlife and Sublime Scenery

Quito to Guayaquil

Cruise Line
Hurtigruten
Cruise Ship
MS Santa Cruz
Departs
4/4/23
From
$6,555
39-night Fiji, French Polynesia, and Hawaii Cruise

Lautoka to Vancouver

Cruise Line
Seabourn
Cruise Ship
Seabourn Odyssey
Departs
4/4/23
 
Call For Pricing
10-night Caribbean – Bermuda and Dominican Republic Cruise

Roundtrip New York City

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Gem
Departs
4/5/23
From
$1,099
17-night Easter Island to Tahiti – Tales of the Pacific Cruisetour

Papeete to Santiago

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Orion
Departs
4/5/23
From
$21,280
28-night South Pacific Seascapes Voyage

Papeete to Los Angeles

Cruise Line
Oceania Cruises
Cruise Ship
Regatta
Departs
4/6/23
From
$11,449
10-night Quito and Galápagos Southern Loop Cruisetour

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Xpedition
Departs
4/6/23
 
Call For Pricing
11-night Quito and Galápagos Southern Loop Cruisetour

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Xpedition
Departs
4/6/23
 
Call For Pricing
16-night Galápagos Southern Loop and Machu Picchu Cruisetour

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Xpedition
Departs
4/6/23
 
Call For Pricing
10-night Quito and Galápagos Northern Loop Cruisetour

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
4/6/23
 
Call For Pricing
11-night Quito and Galápagos Northern Loop Cruisetour

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
4/6/23
 
Call For Pricing
16-night Galápagos Northern Loop and Machu Picchu Cruisetour

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
4/6/23
 
Call For Pricing
9-night Western Caribbean Cruise

Roundtrip Galveston

Cruise Line
Royal Caribbean International
Cruise Ship
Radiance of the Seas
Departs
4/6/23
10-night Machu Picchu, National Parks, and the Panama Canal Expedition

Lima to Colon (Panama)

Cruise Line
Hurtigruten
Cruise Ship
MS Fram
Departs
4/6/23
 
Call For Pricing
16-night Galápagos Outer Loop and Machu Picchu Cruisetour

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Flora
Departs
4/7/23
 
Call For Pricing
11-night Quito and Galápagos Outer Loop Cruisetour

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Flora
Departs
4/7/23
From
$12,574
23-night Transoceanic Cruise

Rio de Janeiro to Lisbon

Cruise Line
Silversea Cruises
Cruise Ship
Silver Wind
Departs
4/7/23
From
$8,350
34-night Transoceanic Cruise

Rio de Janeiro to London

Cruise Line
Silversea Cruises
Cruise Ship
Silver Wind
Departs
4/7/23
 
Call For Pricing
9-night Galápagos Cruise/Land Package

Roundtrip Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Endeavour II
Departs
4/7/23
From
$8,100
14-night East & West Galapagos Cruise

Roundtrip Isla Baltra

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
4/7/23
 
Call For Pricing
5-night Baja Cruise

Roundtrip San Diego

Cruise Line
Disney Cruise Line
Cruise Ship
Disney Wonder
Departs
4/7/23
 
Call For Pricing
« Previous