Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

5,001 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

7-night East Galapagos Cruise - Isla Baltra to Puerto Ayora

Isla Baltra to Puerto Ayora

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
5/3/24
 
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14-night East & West Galapagos Cruise - Roundtrip Isla Baltra

Roundtrip Isla Baltra

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
5/3/24
 
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11-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
5/3/24
From
$16,139
16-night Galapagos Outer Loop & Machu Picchu Cruise/Land Package

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
5/3/24
 
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10-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
5/3/24
From
$16,019
7-night Amazon Expedition Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aria Amazon
Departs
5/3/24
 
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3-night Amazon Discovery Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aria Amazon
Departs
5/3/24
 
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15-night Galápagos and Peru's Land of the Inca Cruise/Land Package

Guayaquil to Lima

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Endeavour II
Departs
5/3/24
From
$14,961
9-night Galápagos Cruise/Land Package

Roundtrip Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Endeavour II
Departs
5/3/24
From
$8,761
3-night Amazon Discovery Cruise - Iquitos to Nauta

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
5/4/24
 
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7-night Amazon Expedition Cruise - Roundtrip Iquitos

Roundtrip Iquitos

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
5/4/24
 
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7-night Galapagos Southern Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xpedition
Departs
5/4/24
From
$8,899
7-night Galápagos Northern Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
5/4/24
 
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7-night Galápagos Islands Cruise

Roundtrip Isla San Cristobal (Puerto Baquerizo Moreno)

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
5/4/24
 
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9-night Upper Amazon Cruise

Roundtrip Lima

Cruise Line
Lindblad Expeditions
Cruise Ship
Delfin II
Departs
5/4/24
From
$8,865
7-night Wild Galapagos Escape Cruise

Roundtrip Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Islander II
Departs
5/4/24
From
$10,908
6-night Galápagos Islands - Nature and Wildlife Expedition Cruise

Roundtrip Quito

Cruise Line
Hurtigruten
Cruise Ship
MS Santa Cruz
Departs
5/4/24
From
$6,349
9-night Eastern Caribbean: Dominican Republic & St. Thomas Cruise

Roundtrip Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Sky
Departs
5/5/24
From
$1,129
7-night Galapagos Outer Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
5/5/24
From
$14,019
4-night Baja Cruise

Roundtrip San Diego

Cruise Line
Disney Cruise Line
Cruise Ship
Disney Wonder
Departs
5/5/24
 
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14-night Discover the Galápagos and Peru Cruise/Land Package

Lima to Quito

Cruise Line
Avalon Waterways
Cruise Ship
Treasure of Galápagos
Departs
5/5/24
From
$9,163
19-night Discover the Galápagos and Peru with the Amazon Cruise/Land Package

Lima to Quito

Cruise Line
Avalon Waterways
Cruise Ship
Treasure of Galápagos
Departs
5/5/24
From
$11,510
11-night Galápagos Islands Cruise/Land Package – In Darwin's Footsteps Plus Machu Picchu

Lima to Quito

Cruise Line
Hurtigruten
Cruise Ship
MS Santa Cruz
Departs
5/5/24
From
$9,752
4-night Amazon Explorer Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aria Amazon
Departs
5/6/24
 
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