Mississippi River Cruises

Specials / Mississippi River Cruises
Cruise Line American Cruise Lines
Prices From $1,870
Expires 6/30/19

Cruise the legendary Mississippi River with American Cruise Lines and get InsiderExtras you can't get anywhere else.

Experience the Mississippi River like never before on an all-inclusive river cruise. American Cruise Lines emphasizes the history and culture of the United States with delicious regional cuisine, amazing onboard music, and customized tours to historical landmarks.

Your river cruise always includes:

PLUS, for a limited time, receive a complimentary bottle of wine when you reserve your cruise with us!

Includes free extras and bonus savings available only from CruiseInsider.

7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
12/12/19
 
Call For Pricing
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/16/19
From
$4,320
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
11/9/19
From
$5,245
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
10/26/19
From
$4,270
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
7/6/19
From
$2,595
7-night Upper Mississippi River Cruise

St. Louis to St. Paul

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
9/17/19
From
$4,820
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/2/19
From
$4,745
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
10/26/19
From
$6,275
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/9/19
From
$3,770
7-night Upper Mississippi River Cruise

St. Paul to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
9/4/20
From
$4,620
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
2/23/20
From
$4,530
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
3/8/20
From
$4,730
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
4/5/20
From
$4,830
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
5/24/20
From
$4,930
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
6/7/20
From
$4,315
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
10/12/19
From
$5,580
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
3/1/20
From
$4,530
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
4/12/20
From
$4,930
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
4/26/20
From
$4,930
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
5/17/20
From
$4,630
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
5/31/20
From
$4,930
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
6/21/20
From
$4,315
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
9/28/19
From
$5,245
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
12/12/19
From
$3,705
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
12/20/19
From
$3,805
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
12/28/19
From
$3,805
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
12/12/20
 
Call For Pricing
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
12/28/20
 
Call For Pricing
7-night Upper Mississippi River Cruise

St. Louis to St. Paul

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
8/28/20
From
$4,315
10-night Ohio River Cruise

St. Louis to Pittsburgh

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
8/2/20
From
$4,935
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
7/25/20
From
$2,130
7-night Upper Mississippi River Cruise

St. Paul to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
9/27/20
From
$4,070
7-night Upper Mississippi River Cruise

St. Louis to St. Paul

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
9/20/20
From
$4,070
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
3/21/20
From
$4,340
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
7/29/20
From
$2,130
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/16/20
From
$1,970
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/20/20
From
$1,970
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/24/20
From
$1,970
7-night Upper Mississippi River Cruise

St. Louis to St. Paul

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
10/4/20
From
$4,070
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
2/29/20
From
$3,125
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
3/7/20
From
$3,225
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
7/4/20
From
$3,795
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
7/18/20
From
$3,795
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
12/12/20
 
Call For Pricing
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/4/20
From
$4,040
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/18/20
From
$4,340
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
5/9/20
From
$4,340
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
5/23/20
From
$4,340
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
6/6/20
From
$4,315
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/11/20
From
$4,040
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/25/20
From
$4,340
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
5/16/20
From
$4,340
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
5/30/20
From
$4,340
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
6/13/20
From
$3,795
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
6/27/20
From
$3,795
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
5/3/20
From
$4,620
7-night Cumberland River Cruise

Nashville to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
8/29/20
From
$3,795
7-night Cumberland River Cruise

St. Louis to Nashville

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
8/22/20
From
$3,795
10-night Mississippi River Gateway Cruise

New Orleans to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
6/13/20
From
$5,310
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
4/25/20
From
$3,525
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
3/28/20
From
$4,040
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
4/4/20
From
$4,040
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
3/16/20
From
$1,870
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
3/20/20
From
$1,870
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
3/24/20
From
$1,970
10-night Ohio River Cruise

Pittsburgh to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
8/12/20
From
$4,935
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
11/28/20
From
$3,525
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
4/11/20
From
$4,140
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
5/2/20
From
$4,340
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
5/16/20
From
$4,340
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
5/30/20
From
$4,340
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
4/18/20
From
$4,340
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
5/9/20
From
$4,040
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
5/23/20
From
$4,340
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
11/2/19
From
$4,745
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
11/16/19
From
$4,220
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
11/9/19
From
$4,320
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
11/23/19
From
$4,320
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
7/18/19
From
$4,545
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
7/25/19
From
$4,745
7-night Upper Mississippi River Cruise

St. Paul to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
8/11/19
From
$4,515
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
10/24/20
From
$4,070
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
12/5/20
From
$3,525
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
10/31/20
From
$4,340
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
11/7/20
From
$4,070
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
10/25/20
From
$2,285
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
5/2/20
From
$4,070
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
6/28/20
From
$4,315
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
7/12/20
From
$4,315
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
10/9/20
From
$4,930
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
10/23/20
From
$4,930
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
7/5/20
From
$4,215
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
10/2/20
From
$4,930
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
10/16/20
From
$4,930
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
7/19/20
From
$4,315
7-night New Orleans to New Orleans Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
12/1/20
 
Call For Pricing
7-night Upper Mississippi River Cruise

St. Paul to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
9/11/20
From
$4,620
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
10/29/20
From
$4,340
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
Queen of the Mississippi
Departs
6/6/20
From
$3,795
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/5/20
From
$4,070
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
3/14/21
From
$3,525
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/6/21
From
$4,070
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/13/21
From
$4,070
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/20/21
From
$4,070
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
3/21/21
From
$1,970
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
3/25/21
From
$2,250
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
3/29/21
From
$1,970
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
4/2/21
From
$2,285
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
America
Departs
11/8/21
From
$1,970
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
7/26/20
From
$2,430
4-night Highlights of the Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
11/13/20
From
$2,430
7-night Upper Mississippi River Cruise

St. Paul to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
8/14/21
From
$4,315
7-night Upper Mississippi River Cruise

St. Paul to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
8/28/21
From
$4,315
7-night Upper Mississippi River Cruise

St. Paul to St. Louis

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
9/11/21
From
$4,620
7-night Upper Mississippi River Cruise

St. Louis to St. Paul

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
8/21/21
From
$4,315
7-night Upper Mississippi River Cruise

St. Louis to St. Paul

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
9/4/21
From
$4,620
7-night Upper Mississippi River Cruise

St. Louis to St. Paul

Cruise Line
American Cruise Lines
Cruise Ship
American Harmony
Departs
9/18/21
From
$4,620
7-night Mississippi River Cruise

Roundtrip New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
8/22/20
 
Call For Pricing
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
8/29/20
 
Call For Pricing
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
9/12/20
From
$4,015
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
9/26/20
From
$4,515
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
10/10/20
From
$4,515
7-night Lower Mississippi River Cruise

New Orleans to Memphis

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
10/24/20
From
$4,515
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
9/5/20
 
Call For Pricing
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
9/19/20
From
$4,515
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
10/3/20
From
$4,515
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
10/17/20
From
$4,515
7-night Lower Mississippi River Cruise

Memphis to New Orleans

Cruise Line
American Cruise Lines
Cruise Ship
American Jazz
Departs
10/31/20
From
$4,515

Terms and Conditions

Fares/rates are per person, based on double occupancy for select sail and travel dates; are capacity controlled and subject to availability at time booking and may be pulled without notice. We reserve the right to correct errors. Information and pricing is subject to change without notice. While we do our very best to ensure that information and pricing appearing in this website is complete and accurate, we cannot be responsible for incomplete and inaccurate representations, which may or may not be under our control. In the event of a pricing error, misrepresentation or omission, we reserve the right to adjust the pricing or make any other corrections.

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