Experience the most captivating destinations of the Pacific Northwest cruising along the Columbia and Snake Rivers. Admire the wonders of nature from your private balcony onboard an American Cruise Lines river cruise. Now is the time to treat yourself to a once-in-a-lifetime lifetime journey along the Columbia & Snake Rivers, the perfect blend of scenic landscapes, incredible history, and rich culture. On board relax and enjoy the delicious cuisine, onboard guest speaker presentations, and share the day’s adventures at the daily cocktail hour. And for a limited time receive Free Airfare, Plus Savings up to $1,200 on select sailings!
Your river cruise always includes:
PLUS, for a limited time, receive a complimentary bottle of wine when you reserve your cruise with us!Search the sailings below or contact our experts at 1 (877) 734-6858 to start planning your Alaska cruise with American Cruise Lines.
Submit the form below or call us at 1 (877) 734-6858
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
| 8-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 5/19/24 | Call For Pricing |
| 5-night Highlights of the Columbia River Cruise Roundtrip Hayden Island, Portland | Cruise Line American Cruise Lines | Cruise Ship American Song | Departs 5/28/24 | Call For Pricing |
| 10-night Northwest Pioneers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Jazz | Departs 6/1/24 | From $7,920 |
| 8-night Columbia and Snake Rivers Cruise Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Harmony | Departs 6/6/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Song | Departs 7/2/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 7/14/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Harmony | Departs 8/22/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 9/1/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 9/8/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Hayden Island, Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Harmony | Departs 10/10/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Hayden Island, Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Song | Departs 10/15/24 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 10/27/24 | Call For Pricing |
| 7-night Puget Sound and San Juan Islands Cruise Roundtrip Seattle | Cruise Line American Cruise Lines | Cruise Ship American Constellation | Departs 3/31/25 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 4/6/25 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 4/13/25 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 5/4/25 | Call For Pricing |
| 8-night Columbia and Snake Rivers Cruise Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Pride | Departs 5/11/25 | Call For Pricing |
Fares/rates are per person, based on double occupancy for select sail and travel dates; are capacity controlled and subject to availability at time booking and may be pulled without notice. We reserve the right to correct errors. Information and pricing is subject to change without notice. While we do our very best to ensure that information and pricing appearing in this website is complete and accurate, we cannot be responsible for incomplete and inaccurate representations, which may or may not be under our control. In the event of a pricing error, misrepresentation or omission, we reserve the right to adjust the pricing or make any other corrections.