Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
4,947 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
---|---|---|---|---|
11-night Classic Panama Canal Voyage
Panama City to Miami |
Cruise Line
Oceania Cruises
|
Cruise Ship
Sirena
|
Departs
2/18/25
|
From
$3,599
|
17-night South America and the Chilean Fjords Cruise
Buenos Aires to Santiago (Valparaiso) |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Jupiter (Ocean)
|
Departs
2/18/25
|
From
$6,999
|
11-night Journey to Antarctica – The White Continent Cruise
Roundtrip Santiago |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Resolution
|
Departs
2/18/25
|
From
$18,536
|
6-night Galápagos Islands Expedition Cruise – Iconic Wildlife and Sublime Scenery
Roundtrip Quito |
Cruise Line
Hurtigruten
|
Cruise Ship
MS Santa Cruz
|
Departs
2/18/25
|
From
$5,225
|
10-night Galápagos Islands – Nine of the Best Isles Cruise/Land Package
Roundtrip Quito |
Cruise Line
Hurtigruten
|
Cruise Ship
MS Santa Cruz
|
Departs
2/18/25
|
From
$7,933
|
6-night Wild Galapagos Escape Cruise
Roundtrip Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
2/18/25
|
From
$10,241
|
10-night Antarctic Explorer: Discovering the 7th Continent Expedition
Roundtrip Ushuaia |
Cruise Line
Quark Expeditions
|
Cruise Ship
World Explorer
|
Departs
2/18/25
|
Call For Pricing
|
18-night Iridescent Isles & Inlets Voyage
Roundtrip Miami |
Cruise Line
Oceania Cruises
|
Cruise Ship
Vista
|
Departs
2/19/25
|
From
$7,199
|
14-night South America Passage Cruise
Santiago (San Antonio) to Buenos Aires |
Cruise Line
Holland America Line
|
Cruise Ship
Oosterdam
|
Departs
2/19/25
|
From
$2,149
|
10-night Southern Caribbean Seafarer Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Eurodam
|
Departs
2/19/25
|
From
$1,142
|
11-night Antarctic Explorer – Discovering the 7th Continent Expedition
Roundtrip Buenos Aires |
Cruise Line
Quark Expeditions
|
Cruise Ship
Ultramarine
|
Departs
2/19/25
|
Call For Pricing
|
21-night Southern Caribbean Seafarer / Eastern Wayfarer Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Eurodam
|
Departs
2/19/25
|
From
$3,509
|
10-night Magic of Colombia with 3 nights Medellin Cruise/Land Package
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
2/19/25
|
From
$5,224
|
10-night Peruvian Rivers and Rainforest Discovery Cruise/Land Package
Roundtrip Lima |
Cruise Line
Uniworld River Cruises
|
Cruise Ship
Aria Amazon
|
Departs
2/19/25
|
From
$12,999
|
15-night Peruvian Amazon and Machu Picchu Exploration Cruise/Land Package
Roundtrip Lima |
Cruise Line
Uniworld River Cruises
|
Cruise Ship
Aria Amazon
|
Departs
2/19/25
|
From
$14,499
|
21-night Antarctica, South Georgia, and the Falkland Islands Cruise/Land Package
Roundtrip Buenos Aires |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Endurance
|
Departs
2/20/25
|
From
$34,693
|
16-night Galápagos Southern Loop and Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
2/20/25
|
From
$17,647
|
10-night Quito and Galápagos Southern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
2/20/25
|
From
$9,631
|
11-night Quito and Galápagos Southern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
2/20/25
|
From
$9,775
|
16-night Galápagos Northern Loop and Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
2/20/25
|
From
$17,123
|
8-night Cruising the Galápagos Islands Cruise/Land Package
Roundtrip Guayaquil |
Cruise Line
Tauck Cruises
|
Cruise Ship
Isabela II
|
Departs
2/20/25
|
From
$9,590
|
68-night Longitudinal World Cruise V
Buenos Aires to Milwaukee |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Octantis
|
Departs
2/20/25
|
From
$52,995
|
47-night Antarctica, Chile & the Americas Cruise
Buenos Aires to Ft. Lauderdale |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Octantis
|
Departs
2/20/25
|
From
$38,885
|
12-night Panama Canal Cruise
Miami to Panama City |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Jade
|
Departs
2/20/25
|
Call For Pricing
|