Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

4,910 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

11-nght Quito & Galapagos Northern Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xpedition
Departs
12/5/24
From
$8,279
7-night Antarctic Express – Fly the Drake Expedition

Roundtrip Punta Arenas

Cruise Line
Quark Expeditions
Cruise Ship
World Explorer
Departs
12/5/24
 
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7-night West Galapagos Cruise - Puerto Ayora to Isla Baltra

Puerto Ayora to Isla Baltra

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
12/6/24
 
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14-night West & East Galapagos Cruise - Roundtrip Santa Cruz Island

Puerto Ayora to Isla Baltra

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
12/6/24
 
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10-night Quito & Galapagos Inner Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
12/6/24
From
$9,559
11-night Quito & Galapagos Inner Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
12/6/24
From
$9,679
16-night Galapagos Inner Loop & Machu Picchu Cruise/Land Package

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
12/6/24
From
$16,239
7-night Amazon Expedition Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aria Amazon
Departs
12/6/24
 
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3-night Amazon Discovery Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aria Amazon
Departs
12/6/24
 
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15-night Panama Canal: Mexico & Colombia Cruise

Los Angeles to Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Bliss
Departs
12/6/24
From
$1,049
10-night Wild Galapagos & Peru Escape Cruise

Lima to Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Islander II
Departs
12/6/24
From
$11,233
3-night Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Navigator of the Seas
Departs
12/6/24
9-night Western Caribbean Cruise

Roundtrip Tampa

Cruise Line
Royal Caribbean International
Cruise Ship
Serenade of the Seas
Departs
12/6/24
13-night Antarctica Exploration Cruise

Roundtrip Buenos Aires

Cruise Line
Seabourn
Cruise Ship
Seabourn Venture
Departs
12/6/24
 
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9-night Galápagos Cruise/Land Package

Roundtrip Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Endeavour II
Departs
12/6/24
From
$8,435
15-night Galápagos and Peru's Land of the Inca Cruise/Land Package

Guayaquil to Lima

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Endeavour II
Departs
12/6/24
From
$14,635
11-night Antarctic Explorer – Discovering the 7th Continent Expedition

Roundtrip Buenos Aires

Cruise Line
Quark Expeditions
Cruise Ship
Ultramarine
Departs
12/6/24
 
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12-night Panama Canal With Costa Rica & Caribbean Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Emerald Princess
Departs
12/6/24
 
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7-night Key West, Bimini, Labadee Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Apex
Departs
12/7/24
From
$1,226
10-night Classic Panama Canal Passage Cruise

Ft. Lauderdale to Fuerte Amador

Cruise Line
Viking Cruises
Cruise Ship
Viking Mars
Departs
12/7/24
From
$3,299
11-night Mexican Riviera & Sea Of Cortez Cruise

Roundtrip San Diego

Cruise Line
Holland America Line
Cruise Ship
Zaandam
Departs
12/7/24
From
$1,007
27-night Mexican Riviera/Sea Of Cortez & Circle Hawaii Cruise

Roundtrip San Diego

Cruise Line
Holland America Line
Cruise Ship
Zaandam
Departs
12/7/24
From
$2,924
7 night St. Maarten, San Juan & Puerto Plata Cruise

Roundtrip Orlando

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Equinox
Departs
12/7/24
From
$1,111
7-night Costa Rica and the Panama Canal Cruise

San Jose (C.R.) to Panama City

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Quest
Departs
12/7/24
From
$7,246