Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
5,932 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
10-night Wonders of Colombia with 3 nights in Panama City Cruise/Land Package
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
7/2/25
|
Call For Pricing
|
|
20-night Panoramic Panama Canal - 2025 World Voyage Segment
San Diego to New York City |
Cruise Line
Oceania Cruises
|
Cruise Ship
Insignia
|
Departs
7/3/25
|
From
$5,899
|
|
9-night Wonders of Colombia with 2 nights in Cartagena Cruise/Land Package
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
7/3/25
|
Call For Pricing
|
|
7-night Wild Galapagos Escape Cruise
Roundtrip Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
7/3/25
|
From
$10,250
|
|
10-night Quito and Galápagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
7/4/25
|
Call For Pricing
|
|
11-night Quito and Galápagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
7/4/25
|
Call For Pricing
|
|
16-night Galápagos Inner Loop and Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
7/4/25
|
Call For Pricing
|
|
10-night Caribbean with Bermuda Overnight Cruise
Roundtrip New York City |
Cruise Line
Princess Cruises
|
Cruise Ship
Island Princess
|
Departs
7/4/25
|
From
$2,298
|
|
12-night From the Inca Empire to the Peruvian Amazon with the Nazca Lines Cruise/Land Package
Roundtrip Lima |
Cruise Line
Avalon Waterways
|
Cruise Ship
Delfin III
|
Departs
7/4/25
|
From
$7,397
|
|
10-night Wild Galapagos & Peru Escape Cruise
Lima to Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
7/4/25
|
From
$12,589
|
|
7-night West Galapagos Expedition Cruise
Puerto Ayora to Baltra Island |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
7/4/25
|
Call For Pricing
|
|
14-night West & East Galapagos Expedition Cruise
Roundtrip Puerto Ayora |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
7/4/25
|
Call For Pricing
|
|
9-night Eastern Caribbean & Perfect Day Cruise
Roundtrip Cape Liberty Cruise Port (Bayonne, NJ) |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Symphony of the Seas
|
Departs
7/4/25
|
From
$2,678
|
|
7-night Cabo, Vallarta & Mazatlan Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Navigator of the Seas
|
Departs
7/4/25
|
From
$1,221
|
|
19-night From The Inca Empire To The Peruvian Amazon With The Nazca Lines & Galápagos Cruise/Land Package
Lima to Quito |
Cruise Line
Avalon Waterways
|
Cruise Ship
Delfin III
|
Departs
7/4/25
|
Call For Pricing
|
|
15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Endeavour II
|
Departs
7/4/25
|
From
$13,111
|
|
9-night Exploring Galápagos: One Week Sailing The Islands Cruise/Land Package
Roundtrip Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Endeavour II
|
Departs
7/4/25
|
From
$7,073
|
|
5-night Cabo Overnight Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Ovation of the Seas
|
Departs
7/4/25
|
From
$927
|
|
9-night Galápagos By Catamaran: An Intimate Voyage Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Delfina
|
Departs
7/4/25
|
From
$9,242
|
|
15-night Galápagos By Catamaran + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Quito or Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Delfina
|
Departs
7/4/25
|
From
$15,280
|
|
15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Quito or Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Gemini
|
Departs
7/4/25
|
From
$13,648
|
|
9-night Exploring Galápagos: One Week Sailing The Islands Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Gemini
|
Departs
7/4/25
|
From
$7,610
|
|
14-night Caribbean East/West Adventurer Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Princess Cruises
|
Cruise Ship
Enchanted Princess
|
Departs
7/5/25
|
From
$4,018
|
|
7-night Eastern Caribbean: Great Stirrup Cay & Dominican Republic Cruise
Roundtrip Port Canaveral |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian New Build
|
Departs
7/5/25
|
From
$1,559
|