Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

4,910 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

114-night World Cruise - Roundtrip Sydney

Roundtrip Sydney

Cruise Line
Princess Cruises
Cruise Ship
Crown Princess
Departs
5/10/26
 
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9-night Hawaii Cruise

Honolulu to Vancouver

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Edge
Departs
5/7/26
From
$1,426
18-night Panama Canal - Ocean To Ocean Cruise

Los Angeles to New York

Cruise Line
Princess Cruises
Cruise Ship
Island Princess
Departs
5/6/26
 
Call For Pricing
114-night World Cruise - Roundtrip Auckland

Roundtrip Auckland

Cruise Line
Princess Cruises
Cruise Ship
Crown Princess
Departs
5/6/26
 
Call For Pricing
17-night Northern Pacific Journey Cruise – Tokyo to Vancouver

Tokyo to Vancouver

Cruise Line
Regent Seven Seas Cruises
Cruise Ship
Seven Seas Explorer
Departs
5/3/26
From
$14,699
7-night Galapagos Outer Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
5/3/26
From
$7,999
11-night Hawaii & Pacific Crossing: Honolulu to British Columbia Cruise

Honolulu to Vancouver

Cruise Line
Princess Cruises
Cruise Ship
Grand Princess
Departs
4/28/26
10-night Pacific Crossing: Honolulu to British Columbia Cruise

Honolulu to Vancouver

Cruise Line
Princess Cruises
Cruise Ship
Discovery Princess
Departs
4/26/26
From
$1,009
15-night North Pacific Crossing Cruise

Yokohama to Vancover

Cruise Line
Holland America Line
Cruise Ship
Westerdam
Departs
4/26/26
From
$2,449
7-night Galapagos Inner Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/26/26
From
$7,999
7-night Mexican Riviera Cruise

Roundtrip San Diego

Cruise Line
Holland America Line
Cruise Ship
Zaandam
Departs
4/25/26
From
$1,249
11-night Mexican Riviera & Pacific Coast Cruise

San Diego to Vancouver

Cruise Line
Holland America Line
Cruise Ship
Zaandam
Departs
4/25/26
From
$1,749
9-night Hawaii Cruise

Honolulu to Vancouver

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Solstice
Departs
4/24/26
From
$1,740
22-night World Segment Cruise: Golden Week To Glacier Bay

Yokohama (Tokyo) to Vancouver

Cruise Line
Seabourn
Cruise Ship
Seabourn Sojourn
Departs
4/24/26
From
$7,064
10-night Canal & Coral Isles Voyage

Panama City to Miami

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
4/24/26
From
$2,999
3-night Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Quantum of the Seas
Departs
4/21/26
18-night Tahitian Treasures Cruise

Sydney to Honolulu

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Edge
Departs
4/20/26
From
$3,987
36-night Beyond The Bering Strait Voyage

Singapore to Seattle

Cruise Line
Oceania Cruises
Cruise Ship
Riviera
Departs
4/20/26
From
$10,699
31-night Asian Lights and Alaskan Sights Cruise – Tokyo to Vancouver

Tokyo to Vancouver

Cruise Line
Regent Seven Seas Cruises
Cruise Ship
Seven Seas Explorer
Departs
4/19/26
From
$26,099
7-night Virgin Islands & Puerto Plata Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xcel
Departs
4/19/26
From
$1,450
7-night Classic California Coast Cruise

Roundtrip San Francisco

Cruise Line
Princess Cruises
Cruise Ship
Ruby Princess
Departs
4/19/26
 
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7-night Galapagos Outer Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/19/26
From
$7,999
7-night Key West, Bahamas & Labadee Cruise

Roundtrip Port Canaveral

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Apex
Departs
4/18/26
From
$1,246
7-night Mexican Riviera Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Royal Princess
Departs
4/18/26
 
Call For Pricing