Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
6,368 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
11-night Quito & Galapagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
5/7/27
|
Call For Pricing
|
|
10-night Quito & Galapagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
5/7/27
|
Call For Pricing
|
|
14-night West & East Galapagos Expedition Cruise
Roundtrip Puerto Ayora |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
5/7/27
|
Call For Pricing
|
|
14-night 2027 World Cruise Segment
Tokyo to Anchorage (Seward) |
Cruise Line
Crystal Cruises
|
Cruise Ship
Crystal Serenity
|
Departs
5/8/27
|
Call For Pricing
|
|
7-night Wonders Of Colombia Cruise
Cartagena to Baranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
5/8/27
|
From
$3,549
|
|
13-night 2027 World Cruise Segment
Yokohama (Tokyo) to Anchorage (Seward) |
Cruise Line
Crystal Cruises
|
Cruise Ship
Crystal Serenity
|
Departs
5/8/27
|
From
$4,900
|
|
7-night Amazon Expeditions Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
5/8/27
|
Call For Pricing
|
|
3-night Amazon Discovery Cruise
Iquitos to Nauta |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
5/8/27
|
Call For Pricing
|
|
7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package
Medellin to Cartagena (Colombia) |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
5/9/27
|
From
$5,109
|
|
7-night Galapagos Inner Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
5/9/27
|
From
$12,292
|
|
17-night Japan & Alaska Cruise
Tokyo to Vancouver |
Cruise Line
Silversea Cruises
|
Cruise Ship
Silver Moon
|
Departs
5/11/27
|
From
$6,550
|
|
19-night World Cruise: Panama Canal Crossing Cruise
Los Angeles (Long Beach Cruise Terminal) to Miami |
Cruise Line
Seabourn
|
Cruise Ship
Seabourn Quest
|
Departs
5/11/27
|
From
$9,134
|
|
4-night Amazon Explorer Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
5/11/27
|
Call For Pricing
|
|
7-night Magic Of Colombia Cruise
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
5/12/27
|
From
$3,549
|
|
7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package
Medellin to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
5/12/27
|
From
$5,109
|
|
10-night In Steinbeck's Wake: An Epic Voyage Through the Sea of Cortez Cruise
Roundtrip San Jose del Cabo |
Cruise Line
UnCruise Adventures
|
Cruise Ship
Safari Voyager
|
Departs
5/13/27
|
Call For Pricing
|
|
7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package
Medellin to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
5/14/27
|
From
$6,099
|
|
10-night Quito & Galapagos Outer Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
5/14/27
|
Call For Pricing
|
|
11-night Quito & Galapagos Outer Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
5/14/27
|
Call For Pricing
|
|
16-night Galapagos Outer Loop & Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
5/14/27
|
Call For Pricing
|
|
7-night East Galapagos Expedition Cruise
Baltra Island to Puerto Ayora |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
5/14/27
|
Call For Pricing
|
|
14-night East & West Galapagos Expedition Cruise
Roundtrip Baltra Island |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
5/14/27
|
Call For Pricing
|
|
7-night Magic Of Colombia Cruise
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
5/15/27
|
From
$3,549
|
|
7-night Amazon Expeditions Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
5/15/27
|
Call For Pricing
|