Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,364 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

7-night Magic Of Colombia Cruise

Barranquilla to Cartagena

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
4/14/27
From
$3,649
7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package

Medellin to Cartagena

Cruise Line
AmaWaterways
Cruise Ship
AmaMagdalena
Departs
4/14/27
From
$5,209
3-night Ensenada Cruise

Roundtrip San Diego

Cruise Line
Royal Caribbean International
Cruise Ship
Serenade of the Seas
Departs
4/15/27
8-night Cabo Overnight, Mazatlan & Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Voyager of the Seas
Departs
4/15/27
From
$1,022
27-night World Cruise: South Pacific Explorer & Hawaii Cruise

Brisbane to Los Angeles (Long Beach Cruise Terminal)

Cruise Line
Seabourn
Cruise Ship
Seabourn Quest
Departs
4/15/27
From
$14,469
7-night Spain & Portugal Discovery Cruise

Lisbon to Barcelona

Cruise Line
Viking Cruises
Cruise Ship
Viking Neptune
Departs
4/16/27
 
Call For Pricing
3-night Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Ovation of the Seas
Departs
4/16/27
7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package

Medellin to Barranquilla

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
4/16/27
From
$6,199
10-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/16/27
 
Call For Pricing
11-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/16/27
 
Call For Pricing
16-night Galapagos Outer Loop & Machu Picchu Cruise/Land Package

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/16/27
 
Call For Pricing
7-night East Galapagos Expedition Cruise

Baltra Island to Puerto Ayora

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
4/16/27
 
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14-night East & West Galapagos Expedition Cruise

Roundtrip Baltra Island

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
4/16/27
 
Call For Pricing
7-night Mexican Riviera Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Discovery Princess
Departs
4/17/27
From
$1,029
7-night Magic Of Colombia Cruise

Barranquilla to Cartagena

Cruise Line
AmaWaterways
Cruise Ship
AmaMagdalena
Departs
4/17/27
From
$3,649
8-nights Southern Caribbean & Perfect Day Cruise

Roundtrip Ft.Lauderdale

Cruise Line
Royal Caribbean International
Cruise Ship
Legend of the Seas
Departs
4/17/27
From
$2,087
5-night Western Caribbean Cruise

Roundtrip Galveston

Cruise Line
Royal Caribbean International
Cruise Ship
Liberty of the Seas
Departs
4/17/27
7-night St. Thomas & St. Kitts Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Beyond
Departs
4/18/27
From
$1,497
30-night South Pacific & Transpacific Cruise

Papeete to Vancouver

Cruise Line
Silversea Cruises
Cruise Ship
Silver Whisper
Departs
4/18/27
 
Call For Pricing
4-night Catalina & Ensenada Cruise

Roundtrip San Diego

Cruise Line
Royal Caribbean International
Cruise Ship
Serenade of the Seas
Departs
4/18/27
7-night Southern Caribbean Cruise

Roundtrip Cartagena (Columbia)

Cruise Line
Royal Caribbean International
Cruise Ship
Jewel of the Seas
Departs
4/18/27
From
$1,287
7-night Galapagos Outer Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/18/27
From
$11,714
7-night Mexican Riviera Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Star Princess
Departs
4/19/27
From
$1,919
4-night Catalina & Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Ovation of the Seas
Departs
4/19/27