Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
6,368 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
7-night Mexican Riviera Cruise
Roundtrip Los Angeles |
Cruise Line
Princess Cruises
|
Cruise Ship
Discovery Princess
|
Departs
4/3/27
|
From
$1,029
|
|
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan
Roundtrip Galveston |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Viva
|
Departs
4/3/27
|
Call For Pricing
|
|
7-night Magic Of Colombia Cruise
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
4/3/27
|
From
$3,649
|
|
5-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Liberty of the Seas
|
Departs
4/3/27
|
From
$573
|
|
7-night Southern Caribbean Cruise
Roundtrip Colon (Panama) |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Jewel of the Seas
|
Departs
4/3/27
|
From
$1,223
|
|
7-night Amazon Expeditions Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
4/3/27
|
Call For Pricing
|
|
3-night Amazon Discovery Cruise
Iquitos to Nauta |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
4/3/27
|
Call For Pricing
|
|
16-night Hawaiian Islands Cruise
Roundtrip Los Angeles |
Cruise Line
Princess Cruises
|
Cruise Ship
Emerald Princess
|
Departs
4/4/27
|
From
$2,449
|
|
7-night St. Thomas & St. Kitts Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Beyond
|
Departs
4/4/27
|
From
$1,677
|
|
7-night Tortola & St. Maarten Holiday Cruise
Roundtrip Miami |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xcel
|
Departs
4/4/27
|
From
$1,580
|
|
16-night Panama Canal Cruise - Ocean To Ocean
Ft. Lauderdale to Los Angeles |
Cruise Line
Princess Cruises
|
Cruise Ship
Crown Princess
|
Departs
4/4/27
|
From
$2,136
|
|
7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta
Roundtrip Los Angeles |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Encore
|
Departs
4/4/27
|
From
$1,091
|
|
4-night Catalina & Ensenada Cruise
Roundtrip San Diego |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Serenade of the Seas
|
Departs
4/4/27
|
From
$514
|
|
7-night Southern Caribbean Cruise
Roundtrip Cartagena (Columbia) |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Jewel of the Seas
|
Departs
4/4/27
|
From
$1,287
|
|
7-night Galapagos Outer Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
4/4/27
|
From
$11,714
|
|
4-night Catalina & Ensenada Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Ovation of the Seas
|
Departs
4/5/27
|
From
$491
|
|
7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package
Medellin to Baranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
4/5/27
|
From
$6,199
|
|
7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package
Cartagena (Colombia) to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
4/5/27
|
From
$4,639
|
|
10-night Baja California Discovery: Exploring Mexico’s Gulf of California Cruise
Loreto to San Jose del Cabo |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Venture
|
Departs
4/6/27
|
From
$10,128
|
|
10-night Eastern Caribbean With St. Kitts Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Princess Cruises
|
Cruise Ship
Enchanted Princess
|
Departs
4/6/27
|
From
$1,749
|
|
4-night Amazon Explorer Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
4/6/27
|
Call For Pricing
|
|
7-night Wonders Of Colombia Cruise
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
4/7/27
|
From
$3,649
|
|
5-night Western Caribbean Cruise
Roundtrip Port Canaveral |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Explorer of the Seas
|
Departs
4/7/27
|
From
$630
|
|
17-night Circle Hawaii Cruise
Roundtrip Vancouver |
Cruise Line
Holland America Line
|
Cruise Ship
Koningsdam
|
Departs
4/7/27
|
From
$3,424
|