Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
6,368 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
---|---|---|---|---|
7-night Classic California Coast Cruise
Roundtrip Los Angeles |
Cruise Line
Princess Cruises
|
Cruise Ship
Emerald Princess
|
Departs
3/28/27
|
From
$1,129
|
7-night St. Thomas & St. Kitts Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Beyond
|
Departs
3/28/27
|
From
$1,677
|
29-night Legendary South Pacific Crossing: Sydney To Seattle Cruise
Sydney to Seattle |
Cruise Line
Holland America Line
|
Cruise Ship
Noordam
|
Departs
3/28/27
|
From
$5,584
|
7-night Caribbean Cruise: Great Stirrup Cay & Dominican Republic
Roundtrip Miami |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian New Build
|
Departs
3/28/27
|
From
$1,373
|
7-night Caribbean Cruise: Curacao & Aruba
Roundtrip San Juan |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Breakaway
|
Departs
3/28/27
|
From
$1,112
|
7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta
Roundtrip Los Angeles |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Encore
|
Departs
3/28/27
|
From
$1,141
|
7-night Caribbean Cruise: Great Stirrup Cay & Cozumel
Roundtrip Port Canaveral |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Epic
|
Departs
3/28/27
|
From
$991
|
7-night Caribbean Cruise: Dominican Republic & Bahamas
Roundtrip Jacksonville |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Gem
|
Departs
3/28/27
|
From
$980
|
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan
Roundtrip New Orleans |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Prima
|
Departs
3/28/27
|
From
$1,258
|
20-night Tahiti, Hawaii & South Pacific Crossing Cruise
Sydney to Honolulu |
Cruise Line
Princess Cruises
|
Cruise Ship
Royal Princess
|
Departs
3/28/27
|
From
$3,216
|
26-night Tahiti, Hawaii & South Pacific Crossing Cruise
Sydney to Los Angeles |
Cruise Line
Princess Cruises
|
Cruise Ship
Royal Princess
|
Departs
3/28/27
|
From
$3,889
|
32-night Tahiti, Hawaii & South Pacific Crossing Cruise
Sydney to Vancouver |
Cruise Line
Princess Cruises
|
Cruise Ship
Royal Princess
|
Departs
3/28/27
|
From
$5,176
|
7-night Western Caribbean Cruise
Roundtrip Tampa |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Enchantment of the Seas
|
Departs
3/28/27
|
Call For Pricing
|
7-night Ensenada, Cabo & La Paz Cruise
Roundtrip San Diego |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Serenade of the Seas
|
Departs
3/28/27
|
From
$835
|
7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package
Medellin to Cartagena (Colombia) |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
3/28/27
|
From
$5,709
|
7-night Eastern Caribbean Cruise
Roundtrip Miami |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Allure of the Seas
|
Departs
3/28/27
|
From
$1,117
|
7-night Southern Caribbean Cruise
Roundtrip Cartagena (Columbia) |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Jewel of the Seas
|
Departs
3/28/27
|
From
$1,357
|
7-night Galapagos Inner Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
3/28/27
|
From
$9,714
|
4-night Catalina & Ensenada Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Ovation of the Seas
|
Departs
3/29/27
|
From
$521
|
5-night Western Caribbean Cruise
Roundtrip Miami |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Freedom of the Seas
|
Departs
3/29/27
|
From
$621
|
5-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Liberty of the Seas
|
Departs
3/29/27
|
From
$570
|
12-night Panama, Colombia & Caribbean Islands Cruise
Colon (Panama) to Fort de France |
Cruise Line
Ponant Cruises
|
Cruise Ship
Le Bellot
|
Departs
3/29/27
|
From
$7,620
|
4-night Amazon Explorer Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
3/30/27
|
Call For Pricing
|
7-night Magic Of Colombia Cruise
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
3/31/27
|
From
$4,149
|