Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,368 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

7-night Classic California Coast Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Emerald Princess
Departs
3/28/27
From
$1,129
7-night St. Thomas & St. Kitts Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Beyond
Departs
3/28/27
From
$1,677
29-night Legendary South Pacific Crossing: Sydney To Seattle Cruise

Sydney to Seattle

Cruise Line
Holland America Line
Cruise Ship
Noordam
Departs
3/28/27
From
$5,584
7-night Caribbean Cruise: Great Stirrup Cay & Dominican Republic

Roundtrip Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian New Build
Departs
3/28/27
From
$1,373
7-night Caribbean Cruise: Curacao & Aruba

Roundtrip San Juan

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Breakaway
Departs
3/28/27
From
$1,112
7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta

Roundtrip Los Angeles

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Encore
Departs
3/28/27
From
$1,141
7-night Caribbean Cruise: Great Stirrup Cay & Cozumel

Roundtrip Port Canaveral

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Epic
Departs
3/28/27
7-night Caribbean Cruise: Dominican Republic & Bahamas

Roundtrip Jacksonville

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Gem
Departs
3/28/27
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip New Orleans

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Prima
Departs
3/28/27
From
$1,258
20-night Tahiti, Hawaii & South Pacific Crossing Cruise

Sydney to Honolulu

Cruise Line
Princess Cruises
Cruise Ship
Royal Princess
Departs
3/28/27
From
$3,216
26-night Tahiti, Hawaii & South Pacific Crossing Cruise

Sydney to Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Royal Princess
Departs
3/28/27
From
$3,889
32-night Tahiti, Hawaii & South Pacific Crossing Cruise

Sydney to Vancouver

Cruise Line
Princess Cruises
Cruise Ship
Royal Princess
Departs
3/28/27
From
$5,176
7-night Western Caribbean Cruise

Roundtrip Tampa

Cruise Line
Royal Caribbean International
Cruise Ship
Enchantment of the Seas
Departs
3/28/27
 
Call For Pricing
7-night Ensenada, Cabo & La Paz Cruise

Roundtrip San Diego

Cruise Line
Royal Caribbean International
Cruise Ship
Serenade of the Seas
Departs
3/28/27
7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package

Medellin to Cartagena (Colombia)

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
3/28/27
From
$5,709
7-night Eastern Caribbean Cruise

Roundtrip Miami

Cruise Line
Royal Caribbean International
Cruise Ship
Allure of the Seas
Departs
3/28/27
From
$1,117
7-night Southern Caribbean Cruise

Roundtrip Cartagena (Columbia)

Cruise Line
Royal Caribbean International
Cruise Ship
Jewel of the Seas
Departs
3/28/27
From
$1,357
7-night Galapagos Inner Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
3/28/27
From
$9,714
4-night Catalina & Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Ovation of the Seas
Departs
3/29/27
5-night Western Caribbean Cruise

Roundtrip Miami

Cruise Line
Royal Caribbean International
Cruise Ship
Freedom of the Seas
Departs
3/29/27
5-night Western Caribbean Cruise

Roundtrip Galveston

Cruise Line
Royal Caribbean International
Cruise Ship
Liberty of the Seas
Departs
3/29/27
12-night Panama, Colombia & Caribbean Islands Cruise

Colon (Panama) to Fort de France

Cruise Line
Ponant Cruises
Cruise Ship
Le Bellot
Departs
3/29/27
From
$7,620
4-night Amazon Explorer Cruise

Roundtrip Iquitos

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
3/30/27
 
Call For Pricing
7-night Magic Of Colombia Cruise

Barranquilla to Cartagena

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
3/31/27
From
$4,149