Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
6,364 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
17-night Panama & Scenic South America Cruise
Santiago (Valparaiso) to Ft. Lauderdale |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Polaris
|
Departs
3/22/27
|
Call For Pricing
|
|
4-night Catalina & Ensenada Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Ovation of the Seas
|
Departs
3/22/27
|
From
$521
|
|
7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package
Cartagena (Colombia) to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
3/22/27
|
From
$4,739
|
|
11-night Southern Caribbean Cruise: Abc Islands
Roundtrip Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Eurodam
|
Departs
3/23/27
|
From
$1,802
|
|
4-night Amazon Explorer Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
3/23/27
|
Call For Pricing
|
|
7-night Wonders Of Colombia Cruise
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
3/24/27
|
From
$3,749
|
|
16-night Inca & Panama Canal Discovery: Lima Overnight Cruise
Santiago (San Antonio) to Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Oosterdam
|
Departs
3/24/27
|
From
$3,764
|
|
12-night Panama Canal Cruise: Mexico, Jamaica & Costa Rica
Roundtrip Miami |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Sun
|
Departs
3/24/27
|
From
$1,928
|
|
5-night Western Caribbean Cruise
Roundtrip Port Canaveral |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Explorer of the Seas
|
Departs
3/24/27
|
From
$766
|
|
7-night Wild Galapagos Escape Cruise
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
3/25/27
|
From
$13,321
|
|
3-night Ensenada Cruise
Roundtrip San Diego |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Serenade of the Seas
|
Departs
3/25/27
|
From
$437
|
|
7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package
Cartagena to Baranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
3/25/27
|
From
$4,639
|
|
4-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Liberty of the Seas
|
Departs
3/25/27
|
From
$534
|
|
9-night Galápagos By Catamaran: An Intimate Voyage Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Delfina
|
Departs
3/26/27
|
From
$15,833
|
|
15-night Galápagos By Catamaran + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Quito or Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Delfina
|
Departs
3/26/27
|
From
$22,052
|
|
15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Quito or Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Gemini
|
Departs
3/26/27
|
From
$16,566
|
|
9-night Exploring Galápagos: One Week Sailing The Islands Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Gemini
|
Departs
3/26/27
|
From
$10,347
|
|
15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Quito or Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Endeavour II
|
Departs
3/26/27
|
From
$13,790
|
|
7-night Caribbean Cruise: Great Stirrup Cay & Dominican Republic
Roundtrip Port Canaveral |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Escape
|
Departs
3/26/27
|
From
$1,170
|
|
5-night Caribbean Cruise: Cozumel & Great Stirrup Cay
Roundtrip Port Canaveral |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Getaway
|
Departs
3/26/27
|
From
$865
|
|
3-night Ensenada Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Ovation of the Seas
|
Departs
3/26/27
|
From
$567
|
|
10-night Quito & Galapagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
3/26/27
|
Call For Pricing
|
|
16-night Galapagos Inner Loop & Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
3/26/27
|
Call For Pricing
|
|
14-night West & East Galapagos Expedition Cruise
Roundtrip Puerto Ayora |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
3/26/27
|
Call For Pricing
|