Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,364 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

7-night Wild Galapagos Escape Cruise

Roundtrip Quito or Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Islander II
Departs
3/20/27
From
$13,031
7-night Mexican Riviera Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Discovery Princess
Departs
3/20/27
From
$1,029
14-night Eastern/Western Caribbean Adventurer Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Star Princess
Departs
3/20/27
From
$2,589
7-night Galapagos Islands Cruise

Roundtrip Isla San Cristobal

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
3/20/27
From
$14,450
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip Galveston

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Viva
Departs
3/20/27
From
$1,196
14-night Mexican Riviera & Baja Peninsula Cruise

Roundtrip San Diego

Cruise Line
Holland America Line
Cruise Ship
Koningsdam
Departs
3/20/27
From
$3,184
7-night Southern Caribbean Cruise

Roundtrip Colon (Panama)

Cruise Line
Royal Caribbean International
Cruise Ship
Jewel of the Seas
Departs
3/20/27
From
$1,150
7-night Baja California's Whales & Sealife Cruise

Roundtrip La Paz, Mexico

Cruise Line
UnCruise Adventures
Cruise Ship
Safari Voyager
Departs
3/20/27
 
Call For Pricing
7-night Classic California Coast Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Emerald Princess
Departs
3/21/27
From
$1,117
7-night Caribbean Cruise: Great Stirrup Cay & Dominican Republic

Roundtrip Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian New Build
Departs
3/21/27
From
$1,373
7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta

Roundtrip Los Angeles

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Encore
Departs
3/21/27
From
$1,291
7-night Caribbean Cruise: Great Stirrup Cay & Cozumel

Roundtrip Port Canaveral

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Epic
Departs
3/21/27
7-night Caribbean Cruise: Dominican Republic & Bahamas

Roundtrip Jacksonville

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Gem
Departs
3/21/27
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip New Orleans

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Prima
Departs
3/21/27
From
$1,258
7-night Western Caribbean Cruise

Roundtrip Tampa

Cruise Line
Royal Caribbean International
Cruise Ship
Enchantment of the Seas
Departs
3/21/27
 
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4-night Catalina & Ensenada Cruise

Roundtrip San Diego

Cruise Line
Royal Caribbean International
Cruise Ship
Serenade of the Seas
Departs
3/21/27
7-night Eastern Caribbean Cruise

Roundtrip Miami

Cruise Line
Royal Caribbean International
Cruise Ship
Independence of the Seas
Departs
3/21/27
From
$1,096
7-night Southern Caribbean Cruise

Roundtrip Cartagena (Columbia)

Cruise Line
Royal Caribbean International
Cruise Ship
Jewel of the Seas
Departs
3/21/27
From
$1,275
7-night Galapagos Outer Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
3/21/27
From
$11,864
21-night Panama Canal & Southern Caribbean Cruise: Abc Islands

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Nieuw Amsterdam
Departs
3/21/27
From
$4,969
12-night Panama Canal Discovery Cruise: Costa Rica & Greater Antilles

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Nieuw Amsterdam
Departs
3/21/27
From
$2,187
7-night Eastern Caribbean Cruise: Amber Cove & Bahamas

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Nieuw Statendam
Departs
3/21/27
From
$1,654
14-night Eastern Caribbean Cruise: Bahamas & San Juan

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Nieuw Statendam
Departs
3/21/27
From
$3,159
7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package

Medellin to Baranquilla

Cruise Line
AmaWaterways
Cruise Ship
AmaMagdalena
Departs
3/22/27
From
$6,199