Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,368 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

9-night Galápagos By Catamaran: An Intimate Voyage Cruise/Land Package

Roundtrip Quito or Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Delfina
Departs
3/19/27
 
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15-night Galápagos By Catamaran + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package

Quito or Guayaquil to Lima

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Delfina
Departs
3/19/27
 
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15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package

Quito or Guayaquil to Lima

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Gemini
Departs
3/19/27
 
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15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package

Quito or Guayaquil to Lima

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Endeavour II
Departs
3/19/27
 
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13-night Argentina & the Chilean Fjords Cruise

Buenos Aires to Santiago (Valparaiso)

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
3/19/27
From
$8,995
10-night Caribbean Cruise: Curacao, Aruba & Dominican Republic

Roundtrip Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Jewel
Departs
3/19/27
 
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7-night Cabo, Vallarta & Mazatlan Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Voyager of the Seas
Departs
3/19/27
7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package

Medellin to Barranquilla

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
3/19/27
From
$6,299
10-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
3/19/27
 
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11-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
3/19/27
 
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21-night Amazonian Spirit Voyage

Rio de Janeiro to Miami

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
3/19/27
From
$6,299
14-night East & West Galapagos Expedition Cruise

Roundtrip Baltra Island

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
3/19/27
 
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7-night Baja California: Among The Great Whales Cruise

Roundtrip Loreto

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Venture
Departs
3/20/27
 
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7-night Wild Galapagos Escape Cruise

Roundtrip Quito or Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Islander II
Departs
3/20/27
 
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7-night Mexican Riviera Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Discovery Princess
Departs
3/20/27
From
$1,029
14-night Eastern/Western Caribbean Adventurer Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Star Princess
Departs
3/20/27
From
$2,589
7-night Galapagos Islands Cruise

Roundtrip Isla San Cristobal

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
3/20/27
From
$14,450
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip Galveston

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Viva
Departs
3/20/27
 
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5-night Western Caribbean Cruise

Roundtrip Galveston

Cruise Line
Royal Caribbean International
Cruise Ship
Liberty of the Seas
Departs
3/20/27
14-night Mexican Riviera & Baja Peninsula Cruise

Roundtrip San Diego

Cruise Line
Holland America Line
Cruise Ship
Koningsdam
Departs
3/20/27
From
$3,184
18-night Baja Peninsula, Mexican Riviera & Pacific Coast Cruise

San Diego to Vancouver

Cruise Line
Holland America Line
Cruise Ship
Koningsdam
Departs
3/20/27
From
$3,749
7-night Baja Peninsula Cruise

Roundtrip San Diego

Cruise Line
Holland America Line
Cruise Ship
Koningsdam
Departs
3/20/27
From
$1,619
7-night Southern Caribbean Cruise

Roundtrip Colon (Panama)

Cruise Line
Royal Caribbean International
Cruise Ship
Jewel of the Seas
Departs
3/20/27
From
$1,150
7-night Baja California's Whales & Sealife Cruise

Roundtrip La Paz, Mexico

Cruise Line
UnCruise Adventures
Cruise Ship
Safari Voyager
Departs
3/20/27
 
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