Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,368 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

7-night Costa Rica And The Panama Canal Eastbound Cruise

San Jose (C.R.) to Panama City

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Quest
Departs
3/13/27
 
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7-night Yachting the Bahamas Cruise

San Juan to Palm Beach

Cruise Line
SeaDream Yacht Club
Cruise Ship
SeaDream II
Departs
3/13/27
From
$5,719
14-night Eastern/Western Caribbean Adventurer Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Star Princess
Departs
3/13/27
From
$2,609
7-night Galapagos Islands Cruise

Roundtrip Isla San Cristobal

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
3/13/27
From
$14,250
7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta

Roundtrip San Diego

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Star
Departs
3/13/27
 
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7-night Amazon Expeditions Cruise

Roundtrip Iquitos

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
3/13/27
 
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3-night Amazon Discovery Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
3/13/27
 
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7-night Classic California Coast Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Emerald Princess
Departs
3/14/27
From
$1,119
7-night St. Thomas & St. Kitts Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Beyond
Departs
3/14/27
From
$1,677
7-night Puerto Plata & St. Maarten Cruise

Roundtrip Miami

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xcel
Departs
3/14/27
From
$1,661
14-night Eastern/Western Caribbean Adventurer Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Sun Princess
Departs
3/14/27
From
$2,518
7-night Eastern Caribbean Cruise With Puerto Rico

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Sun Princess
Departs
3/14/27
From
$1,299
21-night Southern Atlantic Crossing Cruise

Buenos Aires to Barcelona

Cruise Line
Viking Cruises
Cruise Ship
Viking Jupiter (Ocean)
Departs
3/14/27
From
$5,999
43-night Australia, New Zealand & South Pacific Crossing Cruise

Auckland to Seattle

Cruise Line
Holland America Line
Cruise Ship
Noordam
Departs
3/14/27
From
$8,854
7-night Caribbean Cruise: Great Stirrup Cay & Dominican Republic

Roundtrip Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian New Build
Departs
3/14/27
 
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7-night Caribbean Cruise: Curacao & Aruba

Roundtrip San Juan

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Breakaway
Departs
3/14/27
 
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7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta

Roundtrip Los Angeles

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Encore
Departs
3/14/27
 
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7-night Caribbean Cruise: Great Stirrup Cay & Cozumel

Roundtrip Port Canaveral

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Epic
Departs
3/14/27
 
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7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip New Orleans

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Prima
Departs
3/14/27
 
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4-night Catalina & Ensenada Cruise

Roundtrip San Diego

Cruise Line
Royal Caribbean International
Cruise Ship
Serenade of the Seas
Departs
3/14/27
7-night Magic Of Colombia With 3-nights Medellín Pre Cruise Cruise/Land Package

Medellin to Cartagena (Colombia)

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
3/14/27
From
$5,309
7-night Western Caribbean Cruise

Roundtrip Miami

Cruise Line
Royal Caribbean International
Cruise Ship
Independence of the Seas
Departs
3/14/27
6-night Western Caribbean Cruise

Roundtrip Tampa

Cruise Line
Royal Caribbean International
Cruise Ship
Rhapsody of the Seas
Departs
3/14/27
14-night Western & Eastern Caribbean Cruise: Mexico & Bahamas

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Nieuw Statendam
Departs
3/14/27
From
$3,164