Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
6,368 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
22-night Journey To The Amazon Cruise
Roundtrip Panama City |
Cruise Line
Regent Seven Seas Cruises
|
Cruise Ship
Seven Seas Grandeur
|
Departs
3/9/27
|
From
$13,199
|
|
21-night Caribbean Cruise
Roundtrip Miami |
Cruise Line
Cunard Line
|
Cruise Ship
Queen Elizabeth
|
Departs
3/9/27
|
From
$2,849
|
|
9-night Western Caribbean Cruise
Roundtrip Miami |
Cruise Line
Cunard Line
|
Cruise Ship
Queen Elizabeth
|
Departs
3/9/27
|
From
$1,329
|
|
13-night Argentina & the Chilean Fjords Cruise
Buenos Aires to Santiago (Valparaiso) |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Polaris
|
Departs
3/9/27
|
From
$8,995
|
|
19-night Journey To Austral Lands And Valdes Peninsula Cruise
Roundtrip Buenos Aires |
Cruise Line
Ponant Cruises
|
Cruise Ship
Le Lyrial
|
Departs
3/9/27
|
Call For Pricing
|
|
31-night Panama Canal, Inca & South America: Chilean Fjords Cruise
Buenos Aires to Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Oosterdam
|
Departs
3/9/27
|
From
$6,839
|
|
10-night Antarctic Explorer Expedition: Discovering The 7th Continent
Roundtrip Ushuaia |
Cruise Line
Quark Expeditions
|
Cruise Ship
Ocean Explorer
|
Departs
3/9/27
|
Call For Pricing
|
|
64-night World Cruise: Australia In-Depth, Fiji & Hawaii Cruise
Sydney to Los Angeles (Long Beach Cruise Terminal) |
Cruise Line
Seabourn
|
Cruise Ship
Seabourn Quest
|
Departs
3/9/27
|
From
$33,544
|
|
83-night World Cruise: Australia In-Depth & Panama Canal Cruise
Sydney to Miami |
Cruise Line
Seabourn
|
Cruise Ship
Seabourn Quest
|
Departs
3/9/27
|
From
$44,444
|
|
4-night Amazon Explorer Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
3/9/27
|
Call For Pricing
|
|
16-night Machu Picchu & Mayan Ruins Cruise
Lima (Callao) to Miami |
Cruise Line
Regent Seven Seas Cruises
|
Cruise Ship
Seven Seas Mariner
|
Departs
3/10/27
|
From
$11,699
|
|
7-night Wonders Of Colombia Cruise
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
3/10/27
|
Call For Pricing
|
|
19-night Southern America & Panama Canal Voyage: Lima, Panama City & Cozumel
Santiago (San Antonio) to Miami |
Cruise Line
Azamara Cruises
|
Cruise Ship
Azamara Journey
|
Departs
3/10/27
|
From
$6,109
|
|
9-night Antarctica Cruise
King George Island to Port Williams |
Cruise Line
Silversea Cruises
|
Cruise Ship
Silver Wind
|
Departs
3/10/27
|
From
$15,150
|
|
5-night Western Caribbean Cruise
Roundtrip Port Canaveral |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Explorer of the Seas
|
Departs
3/10/27
|
From
$606
|
|
11-night Antarctic Explorer Expedition: Discovering The 7Th Continent
Roundtrip Buenos Aires |
Cruise Line
Quark Expeditions
|
Cruise Ship
Ultramarine
|
Departs
3/10/27
|
Call For Pricing
|
|
11-night Wild Galápagos And Peru Escape Cruise/Land Package
Lima to Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
3/11/27
|
Call For Pricing
|
|
7-night Wild Galapagos Escape Cruise
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
3/11/27
|
Call For Pricing
|
|
3-night Ensenada Cruise
Roundtrip San Diego |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Serenade of the Seas
|
Departs
3/11/27
|
From
$437
|
|
7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package
Cartagena to Baranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
3/11/27
|
From
$4,739
|
|
4-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Liberty of the Seas
|
Departs
3/11/27
|
From
$544
|
|
15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Quito or Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Gemini
|
Departs
3/12/27
|
Call For Pricing
|
|
10-night Quito & Galapagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
3/12/27
|
Call For Pricing
|
|
16-night Galapagos Inner Loop & Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
3/12/27
|
Call For Pricing
|