Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,368 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

14-night Galapagos Islands Cruise

Roundtrip Isla San Cristobal

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
3/6/27
 
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7-night Galapagos Islands Cruise

Roundtrip Isla San Cristobal

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
3/6/27
From
$14,250
8-night Western Caribbean Cruise

Roundtrip Tampa

Cruise Line
Royal Caribbean International
Cruise Ship
Rhapsody of the Seas
Departs
3/6/27
3-night Amazon Discovery Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
3/6/27
 
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5-night Wild Baja California Escape: The Whales Of Magdalena Bay Cruise

Roundtrip Loreto

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Sea Bird
Departs
3/7/27
 
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7-night St. Thomas & St. Kitts Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Beyond
Departs
3/7/27
From
$1,677
10-night Eastern Caribbean With St. Kitts Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Enchanted Princess
Departs
3/7/27
From
$1,599
14-night Eastern/Western Caribbean Adventurer Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Sun Princess
Departs
3/7/27
From
$2,708
7-night Caribbean Cruise: Great Stirrup Cay & Dominican Republic

Roundtrip Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian New Build
Departs
3/7/27
 
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7-night Caribbean Cruise: Curacao & Aruba

Roundtrip San Juan

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Breakaway
Departs
3/7/27
 
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7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta

Roundtrip Los Angeles

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Encore
Departs
3/7/27
 
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7-night Caribbean Cruise: Great Stirrup Cay & Cozumel

Roundtrip Port Canaveral

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Epic
Departs
3/7/27
 
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7-night Caribbean Cruise: Dominican Republic & Bahamas

Roundtrip Jacksonville

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Gem
Departs
3/7/27
 
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7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip New Orleans

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Prima
Departs
3/7/27
 
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4-night Catalina & Ensenada Cruise

Roundtrip San Diego

Cruise Line
Royal Caribbean International
Cruise Ship
Serenade of the Seas
Departs
3/7/27
7-night Southern Caribbean Cruise

Roundtrip Cartagena (Columbia)

Cruise Line
Royal Caribbean International
Cruise Ship
Jewel of the Seas
Departs
3/7/27
From
$1,239
7-night Galapagos Outer Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
3/7/27
From
$11,714
12-night Bossa Nova Reverie Voyage

Buenos Aires to Rio de Janeiro

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
3/7/27
From
$3,599
33-night Brazil Unbound Voyage

Buenos Aires to Miami

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
3/7/27
From
$9,499
11-nights Panama Canal & Southern Caribbean Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Ascent
Departs
3/8/27
From
$2,722
4-night Catalina & Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Ovation of the Seas
Departs
3/8/27
7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package

Medellin to Baranquilla

Cruise Line
AmaWaterways
Cruise Ship
AmaMagdalena
Departs
3/8/27
From
$6,299
7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package

Cartagena (Colombia) to Barranquilla

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
3/8/27
 
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21-night Caribbean Cruise

Roundtrip Miami

Cruise Line
Cunard Line
Cruise Ship
Queen Elizabeth
Departs
3/9/27
From
$2,849