Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
6,368 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
21-night From The Caribbean To The Amazon Cruise
Roundtrip San Juan |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Sea (Ocean)
|
Departs
12/15/26
|
From
$10,199
|
|
11-night Voyage to Antarctica
Roundtrip Santiago |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Resolution
|
Departs
12/16/26
|
Call For Pricing
|
|
7-night Wonders Of Colombia Cruise
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMelodia
|
Departs
12/16/26
|
From
$3,749
|
|
5-night Western Caribbean Cruise
Roundtrip Port Canaveral |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Explorer of the Seas
|
Departs
12/16/26
|
From
$654
|
|
7-night Wonders Of Colombia With 2-nights In Cartagena Pre Cruise Cruise/Land Package
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
12/17/26
|
From
$4,739
|
|
21-night Caribbean Celebration Cruise
Roundtrip Miami |
Cruise Line
Cunard Line
|
Cruise Ship
Queen Elizabeth
|
Departs
12/17/26
|
From
$3,329
|
|
11-night Wild Galápagos And Peru Escape Cruise/Land Package
Lima to Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
12/17/26
|
Call For Pricing
|
|
7-night Wild Galapagos Escape Cruise
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
12/17/26
|
Call For Pricing
|
|
12-night Panama Canal With Costa Rica & Caribbean Holiday Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Princess Cruises
|
Cruise Ship
Caribbean Princess
|
Departs
12/17/26
|
From
$1,979
|
|
10-night Eastern Caribbean With St. Kitts Holiday Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Princess Cruises
|
Cruise Ship
Enchanted Princess
|
Departs
12/17/26
|
From
$2,019
|
|
10-night Classic Panama Canal Passage Cruise
Fuerte Amador (Panama City) to Ft. Lauderdale |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Mars
|
Departs
12/17/26
|
From
$3,299
|
|
11-night Emblematic Antarctica Cruise/Land Package
Roundtrip Buenos Aires |
Cruise Line
Ponant Cruises
|
Cruise Ship
L'Austral
|
Departs
12/17/26
|
Call For Pricing
|
|
11-night Antarctic Explorer Expedition: Discovering The 7Th Continent
Roundtrip Buenos Aires |
Cruise Line
Quark Expeditions
|
Cruise Ship
Ultramarine
|
Departs
12/17/26
|
Call For Pricing
|
|
4-night Western Caribbean Cruise
Roundtrip Galveston |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Liberty of the Seas
|
Departs
12/17/26
|
From
$564
|
|
9-night Galápagos By Catamaran: An Intimate Voyage Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Delfina
|
Departs
12/18/26
|
Call For Pricing
|
|
9-night Exploring Galápagos: One Week Sailing The Islands Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Endeavour II
|
Departs
12/18/26
|
Call For Pricing
|
|
15-night Exploring Galápagos + Machu Picchu And Peru's Land Of The Inca Cruise/Land Package
Quito or Guayaquil to Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Endeavour II
|
Departs
12/18/26
|
Call For Pricing
|
|
18-night Panama Canal Voyage: Colombia, Costa Rica & Mexico
Miami to San Francisco |
Cruise Line
Azamara Cruises
|
Cruise Ship
Azamara Quest
|
Departs
12/18/26
|
From
$4,889
|
|
5-night Caribbean Cruise: Cozumel & Stirrup Cay
Roundtrip Port Canaveral |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Escape
|
Departs
12/18/26
|
Call For Pricing
|
|
3-night Ensenada Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Ovation of the Seas
|
Departs
12/18/26
|
From
$428
|
|
3-night Ensenada Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Voyager of the Seas
|
Departs
12/18/26
|
From
$416
|
|
10-night Antarctic Explorer Expedition: Discovering The 7th Continent
Roundtrip Ushuaia |
Cruise Line
Quark Expeditions
|
Cruise Ship
Ocean Explorer
|
Departs
12/18/26
|
Call For Pricing
|
|
10-night Quito & Galapagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
12/18/26
|
Call For Pricing
|
|
10-night Secrets Of Central America Cruise
Colon (Panama) to Puntarenas |
Cruise Line
Ponant Cruises
|
Cruise Ship
Le Bellot
|
Departs
12/18/26
|
From
$7,560
|