Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,368 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

9-night Upper Amazon Aboard The Delfin II Cruise

Roundtrip Lima

Cruise Line
Lindblad Expeditions
Cruise Ship
Delfin II
Departs
12/12/26
 
Call For Pricing
7-night Magic of Colombia Cruise

Barranquilla to Cartagena

Cruise Line
AmaWaterways
Cruise Ship
AmaMagdalena
Departs
12/12/26
From
$3,749
7-night Magic Of Colombia With 3-nights Panama Post Cruise Cruise/Land Package

Barranquilla to Panama City

Cruise Line
AmaWaterways
Cruise Ship
AmaMagdalena
Departs
12/12/26
 
Call For Pricing
7-night Wild Galapagos Escape Cruise

Roundtrip Quito or Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Islander II
Departs
12/12/26
 
Call For Pricing
7-night Mexican Riviera Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Discovery Princess
Departs
12/12/26
From
$1,109
8-night Southern Caribbean With Abc Islands Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Regal Princess
Departs
12/12/26
From
$1,109
14-night Southern/Eastern Caribbean Adventurer Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Regal Princess
Departs
12/12/26
From
$2,359
14-night Eastern/Western Caribbean Adventurer Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Star Princess
Departs
12/12/26
From
$2,539
7-night Eastern Caribbean Cruise With Bahamas

Roundtrip Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Star Princess
Departs
12/12/26
From
$1,119
16-night Panama Canal Cruise - Ocean To Ocean Holiday

Ft. Lauderdale to Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Island Princess
Departs
12/12/26
From
$2,559
9-night Central America & Mexico Cruise

Puerto Caldera (Puntarenas) to San Diego

Cruise Line
Crystal Cruises
Cruise Ship
Crystal Serenity
Departs
12/12/26
From
$4,700
7-night Galapagos Islands Cruise

Roundtrip Isla San Cristobal

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
12/12/26
From
$12,750
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip Galveston

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Viva
Departs
12/12/26
 
Call For Pricing
8-nights Southern Caribbean & Perfect Day Cruise

Roundtrip Ft.Lauderdale

Cruise Line
Royal Caribbean International
Cruise Ship
Legend of the Seas
Departs
12/12/26
From
$1,885
5-night Western Caribbean Cruise

Roundtrip Galveston

Cruise Line
Royal Caribbean International
Cruise Ship
Liberty of the Seas
Departs
12/12/26
7-night Southern Caribbean Cruise

Roundtrip Colon (Panama)

Cruise Line
Royal Caribbean International
Cruise Ship
Jewel of the Seas
Departs
12/12/26
From
$1,125
7-night Western Caribbean Cruise

Roundtrip Tampa

Cruise Line
Royal Caribbean International
Cruise Ship
Rhapsody of the Seas
Departs
12/12/26
7-night Costa Rica & Panama Canal Cruise

Puerto Caldera (Puntarenas) to Colon (Panama)

Cruise Line
Windstar Cruises
Cruise Ship
Wind Star
Departs
12/12/26
From
$3,669
7-night Eastern Caribbean Cruise: Amber Cove & Bahamas

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Eurodam
Departs
12/12/26
From
$1,324
14-night Eastern Caribbean Cruise: Bahamas & San Juan Holiday

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Eurodam
Departs
12/12/26
From
$2,884
14-night Western & Eastern Caribbean Cruise: Mexico & Bahamas Holiday

Roundtrip Miami

Cruise Line
Holland America Line
Cruise Ship
Zuiderdam
Departs
12/12/26
From
$2,889
7-night Costa Rica's Pure Life Adventure Cruise

Roundtrip Liberia (C.R.)

Cruise Line
UnCruise Adventures
Cruise Ship
Safari Voyager
Departs
12/12/26
 
Call For Pricing
7-night Amazon Expeditions Cruise

Roundtrip Iquitos

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
12/12/26
 
Call For Pricing
3-night Amazon Discovery Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
12/12/26
 
Call For Pricing