Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
6,133 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
|
9-night Exploring Galápagos: One Week Sailing The Islands Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Gemini
|
Departs
12/18/26
|
From
$11,738
|
|
9-night Exploring Galápagos: One Week Sailing The Islands Cruise/Land Package
Roundtrip Quito or Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Endeavour II
|
Departs
12/18/26
|
From
$8,007
|
|
5-night Caribbean Cruise: Cozumel & Stirrup Cay
Roundtrip Port Canaveral |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Escape
|
Departs
12/18/26
|
From
$683
|
|
10-night Antarctic Explorer Expedition: Discovering The 7th Continent
Roundtrip Buenos Aires |
Cruise Line
Quark Expeditions
|
Cruise Ship
World Voyager
|
Departs
12/18/26
|
Call For Pricing
|
|
16-night Galapagos Inner Loop & Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
12/18/26
|
Call For Pricing
|
|
7-night West Galapagos Expedition Cruise
Puerto Ayora to Baltra Island |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
12/18/26
|
Call For Pricing
|
|
7-night Antarctica Direct: Fly The Drake Passage Cruise
Roundtrip Puerto Natales |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Explorer
|
Departs
12/19/26
|
From
$13,326
|
|
9-night Upper Amazon Aboard The Delfin II Cruise
Roundtrip Lima |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
Delfin II
|
Departs
12/19/26
|
From
$8,303
|
|
7-night Wonders Of Colombia Cruise
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
12/19/26
|
From
$3,749
|
|
8-night Southern Caribbean Holiday Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Adventure of the Seas
|
Departs
12/19/26
|
From
$1,540
|
|
17-night South America & The Chilean Fjords Cruise
Santiago (Valparaiso) to Buenos Aires |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Jupiter (Ocean)
|
Departs
12/19/26
|
From
$6,799
|
|
18-night The Great Austral Loop Cruise/Land Package
Roundtrip Buenos Aires |
Cruise Line
Ponant Cruises
|
Cruise Ship
Le Boreal
|
Departs
12/19/26
|
Call For Pricing
|
|
7-night Galapagos Islands Cruise
Roundtrip Isla San Cristobal |
Cruise Line
Silversea Cruises
|
Cruise Ship
Silver Origin
|
Departs
12/19/26
|
From
$13,250
|
|
7-night Mexican Riviera Cruise: Cabo San Lucas & Puerto Vallarta
Roundtrip San Diego |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Star
|
Departs
12/19/26
|
From
$1,317
|
|
22-night South America & Antarctica Holiday Cruise
Buenos Aires to Santiago(San Antonio) |
Cruise Line
Holland America Line
|
Cruise Ship
Oosterdam
|
Departs
12/19/26
|
From
$5,904
|
|
7-night Baja Peninsula Holiday Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Koningsdam
|
Departs
12/19/26
|
From
$1,764
|
|
14-night Mexican Riviera & Baja Peninsula Holiday Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Koningsdam
|
Departs
12/19/26
|
From
$3,549
|
|
7-night Southern Caribbean Holiday Cruise
Roundtrip Colon (Panama) |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Jewel of the Seas
|
Departs
12/19/26
|
From
$1,168
|
|
7-night Costa Rica & Panama Canal Cruise
Colon (Panama) to Puerto Caldera (Puntarenas) |
Cruise Line
Windstar Cruises
|
Cruise Ship
Wind Star
|
Departs
12/19/26
|
From
$3,669
|
|
7-night Eastern Caribbean Holiday Cruise: Amber Cove & Bahamas
Roundtrip Miami |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
12/19/26
|
From
$1,689
|
|
14-night Eastern Caribbean Cruise: Bahamas & San Juan Holiday
Roundtrip Miami |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
12/19/26
|
From
$3,424
|
|
10-night Monteverde Cloud Forest & Arenal Volcano Cruise/Land Package
Colon (Panama) to San Jose (C.R.) |
Cruise Line
Windstar Cruises
|
Cruise Ship
Wind Star
|
Departs
12/19/26
|
From
$6,069
|
|
36-night Caribbean To Cape Horn Voyage
Miami to Buenos Aires |
Cruise Line
Oceania Cruises
|
Cruise Ship
Insignia
|
Departs
12/19/26
|
From
$10,299
|
|
7-night Amazon Expeditions Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
12/19/26
|
Call For Pricing
|