American Cruise Line is an extraordinary river cruise experience while exploring the historic waterways of the United States. Enjoy spacious accommodations, exceptional cuisine, and the highest level of personalized service on every cruise. And for a limited time, you can enjoy $1,000 savings on select 2021 sailings! But hurry, this deal ends February 28, 2021!
Most cruise lines have temporarily introduced relaxed and revised cancellation policies to ensure you feel confident about sailing and give you the additional time, if needed, to evaluate conditions and provide peace of mind regarding your decision to book travel. Please contact one of our experienced Travel Advisors for more specific information about a particular voyage.
Connect with our American Cruises Line experts at 1 (877) 734-6858 to reserve your stateroom today!
Includes free extras and bonus savings available only from CruiseInsider.
| Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
|---|---|---|---|---|
| 7-night Lower Mississippi River Cruise New Orleans to Memphis | Cruise Line American Cruise Lines | Cruise Ship American Jazz | Departs 5/2/21 | From $4,735 |
| 7-night Columbia and Snake Rivers Cruise Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Harmony | Departs 5/5/21 | From $5,365 |
| 7-night Lower Mississippi River Cruise Memphis to New Orleans | Cruise Line American Cruise Lines | Cruise Ship American Jazz | Departs 5/9/21 | From $5,235 |
| 7-night Cape Codder Cruise Roundtrip Boston | Cruise Line American Cruise Lines | Cruise Ship American Constitution | Departs 5/10/21 | From $4,290 |
| 7-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Harmony | Departs 5/12/21 | From $5,365 |
| 7-night Lower Mississippi River Cruise New Orleans to Memphis | Cruise Line American Cruise Lines | Cruise Ship American Jazz | Departs 5/16/21 | From $5,235 |
| 7-night Cape Codder Cruise Roundtrip Boston | Cruise Line American Cruise Lines | Cruise Ship American Constitution | Departs 5/17/21 | From $4,290 |
| 7-night Columbia and Snake Rivers Cruise Portland to Clarkston | Cruise Line American Cruise Lines | Cruise Ship American Harmony | Departs 5/19/21 | From $5,365 |
| 7-night Lower Mississippi River Cruise Memphis to New Orleans | Cruise Line American Cruise Lines | Cruise Ship American Jazz | Departs 5/23/21 | From $5,235 |
| 7-night Cape Codder Cruise Roundtrip Boston | Cruise Line American Cruise Lines | Cruise Ship American Constitution | Departs 5/24/21 | From $4,290 |
| 7-night Columbia and Snake Rivers Cruise Clarkston to Portland | Cruise Line American Cruise Lines | Cruise Ship American Harmony | Departs 5/26/21 | From $5,865 |
| 7-night Lower Mississippi River Cruise New Orleans to Memphis | Cruise Line American Cruise Lines | Cruise Ship American Jazz | Departs 5/30/21 | From $4,835 |
| 7-night Cape Codder Cruise Roundtrip Boston | Cruise Line American Cruise Lines | Cruise Ship American Constitution | Departs 5/31/21 | From $4,290 |
Fares/rates are per person, based on double occupancy for select sail and travel dates; are capacity controlled and subject to availability at time booking and may be pulled without notice. We reserve the right to correct errors. Information and pricing is subject to change without notice. While we do our very best to ensure that information and pricing appearing in this website is complete and accurate, we cannot be responsible for incomplete and inaccurate representations, which may or may not be under our control. In the event of a pricing error, misrepresentation or omission, we reserve the right to adjust the pricing or make any other corrections.
Contact one of our travel experts to help you plan, perfect, and save on your next cruise!