Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
4,978 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
---|---|---|---|---|
7-night Galapagos Northern Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
5/24/25
|
From
$9,151
|
7-night Wonders of Colombia Cruise
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
5/24/25
|
From
$3,599
|
14-night Caribbean East/West Adventurer Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Princess Cruises
|
Cruise Ship
Enchanted Princess
|
Departs
5/24/25
|
Call For Pricing
|
7-night Galapagos Southern Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
5/24/25
|
From
$6,307
|
10-night Wonders of Colombia with 3 nights in Panama City Cruise/Land Package
Cartagena to Barranquilla |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
5/24/25
|
Call For Pricing
|
7-night Eastern Caribbean Cruise
Roundtrip Port Canaveral |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian New Build
|
Departs
5/24/25
|
Call For Pricing
|
31-night Asia and Alaska Cruise
Yokohama to Seattle |
Cruise Line
Cunard Line
|
Cruise Ship
Queen Elizabeth
|
Departs
5/24/25
|
Call For Pricing
|
3-night Amazon Discovery Cruise
Iquitos to Nauta |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
5/24/25
|
Call For Pricing
|
7-night Amazon Expeditions Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
5/24/25
|
Call For Pricing
|
7-night Galapagos Inner Loop Cruise
Roundtrip Isla Baltra |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
5/25/25
|
From
$9,088
|
10-night From the Inca Empire to the Peruvian Amazon Cruise/Land Package
Roundtrip Lima |
Cruise Line
Avalon Waterways
|
Cruise Ship
Delfin III
|
Departs
5/25/25
|
Call For Pricing
|
7-night Eastern Caribbean Cruise
Roundtrip Miami |
Cruise Line
Norwegian Cruise Line
|
Cruise Ship
Norwegian Escape
|
Departs
5/25/25
|
From
$928
|
6-night Wild Galapagos Escape Cruise
Roundtrip Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
5/27/25
|
From
$8,842
|
4-night Amazon Explorer Cruise
Roundtrip Iquitos |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Nera
|
Departs
5/27/25
|
Call For Pricing
|
57-night Epic Tropical Vistas - 2025 World Cruise Segment
Auckland to New York City |
Cruise Line
Oceania Cruises
|
Cruise Ship
Insignia
|
Departs
5/28/25
|
From
$15,699
|
37-night Polynesian Parade - 2025 World Cruise Segment
Auckland to San Diego |
Cruise Line
Oceania Cruises
|
Cruise Ship
Insignia
|
Departs
5/28/25
|
From
$10,599
|
10-night Magic of Colombia with 3 nights Medellin Cruise/Land Package
Barranquilla to Cartagena |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
5/28/25
|
From
$4,774
|
7-night Magic of Colombia with 3 nights Medellin Pre-Cruise and 3 Nights Panama City Post-Cruise Cruise/Land Package
Medellin to Panama City |
Cruise Line
AmaWaterways
|
Cruise Ship
AmaMagdalena
|
Departs
5/28/25
|
Call For Pricing
|
16-night Galápagos Southern Loop and Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
5/29/25
|
From
$23,447
|
10-night Quito and Galápagos Southern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
5/29/25
|
From
$15,431
|
11-night Quito and Galápagos Southern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
5/29/25
|
From
$15,575
|
16-night Galápagos Northern Loop and Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
5/29/25
|
From
$17,759
|
10-night Quito and Galápagos Northern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
5/29/25
|
From
$9,743
|
11-night Quito and Galápagos Northern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
5/29/25
|
From
$9,887
|