Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

4,999 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

86-night From The Arctic To Antarctica Cruise

Nuuk to Ushuaia

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
9/3/25
From
$109,995
168-night Navigate the World – Away in Wonder Cruise

Roundtrip Miami

Cruise Line
Regent Seven Seas Cruises
Cruise Ship
Seven Seas Mariner
Departs
1/7/25
From
$107,499
154-night The Sense of Adventure: 2026 World Criuise

Roundtrip Miami

Cruise Line
Regent Seven Seas Cruises
Cruise Ship
Seven Seas Mariner
Departs
1/10/26
From
$98,199
150-night Away In Wonder: 2025 World Cruise

Miami to San Francisco

Cruise Line
Regent Seven Seas Cruises
Cruise Ship
Seven Seas Mariner
Departs
1/7/25
From
$96,199
141-night World of Splendor: 2027 World Cruise

Miami to New York City

Cruise Line
Regent Seven Seas Cruises
Cruise Ship
Seven Seas Splendor
Departs
1/11/27
From
$89,799
179-night Viking World Voyage I

Ft. Lauderdale to New York City

Cruise Line
Viking Cruises
Cruise Ship
Viking Sky (Ocean)
Departs
12/19/24
From
$85,995
135-night 2026 World Cruise

Los Angeles to Rome (Civitavecchia)

Cruise Line
Crystal Cruises
Cruise Ship
Crystal Serenity
Departs
1/11/26
From
$84,000
127-night Navigate the World: 2027 World Cruise

Miami to Rome (Civitavecchia)

Cruise Line
Regent Seven Seas Cruises
Cruise Ship
Seven Seas Splendor
Departs
1/11/27
From
$81,799
162-night Viking World Voyage II

Los Angeles to New York City

Cruise Line
Viking Cruises
Cruise Ship
Viking Sky (Ocean)
Departs
1/5/25
From
$80,995
86-night From The Arctic To Antarctica Cruise

Nuuk to Ushuaia

Cruise Line
Viking Cruises
Cruise Ship
Viking Polaris
Departs
9/17/26
From
$75,995
129-Day Ring Of Fire: Hidden Gems Cruise

Los Angeles to Vancouver

Cruise Line
Seabourn
Cruise Ship
Seabourn Sojourn
Departs
1/6/26
From
$75,479
123-night World Cruise 2025: Ft. Lauderdale to Barcelona

Ft. Lauderdale to Barcelona

Cruise Line
Crystal Cruises
Cruise Ship
Crystal Serenity
Departs
1/7/25
From
$66,500
78-night Australia, Asia, and Alaska Cruise

Sydney to Vancouver

Cruise Line
Viking Cruises
Cruise Ship
Viking Orion (Ocean)
Departs
3/21/25
From
$64,095
197-night World Odyssey Voyage

Los Angeles to Miami

Cruise Line
Oceania Cruises
Cruise Ship
Vista
Departs
12/20/25
From
$62,999
200-night Kaleidoscope of Your World - 2025 World Cruise

Miami to New York City

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
1/5/25
From
$60,799
196-night Global Horizons - 2025 World Cruise

Roundtrip Miami

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
1/5/25
From
$60,799
137-night Viking World Cruise

Ft. Lauderdale to London (Greenwich)

Cruise Line
Viking Cruises
Cruise Ship
Viking Sky (Ocean)
Departs
12/19/24
From
$59,995
180-night Around the World Voyage

Roundtrip Miami

Cruise Line
Oceania Cruises
Cruise Ship
Vista
Departs
1/6/26
From
$57,999
120-night Viking World Journeys

Los Angeles to London (Greenwich)

Cruise Line
Viking Cruises
Cruise Ship
Viking Sky (Ocean)
Departs
1/5/25
From
$57,995
22-night In-Depth Antarctica, Falklands, and South Georgia Expedition

Roundtrip Santiago

Cruise Line
Hurtigruten
Cruise Ship
MS Fram
Departs
2/1/25
From
$55,669
180-night Around the World in 180 Days - 2025 World Cruise

Miami to San Diego

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
1/5/25
From
$54,499
68-night Longitudinal World Cruise V

Buenos Aires to Milwaukee

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
2/20/25
From
$52,995
68-night Longitudinal World Cruise VI

Buenos Aires to Milwaukee

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
2/24/26
From
$52,995
95-night Pole to Pole Adventure - The Ultimate Bucket List Expedition Cruise

Vancouver to Buenos Aires

Cruise Line
Hurtigruten
Cruise Ship
MS Roald Amundsen
Departs
8/4/24
From
$50,249
« Previous