Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

6,368 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

7-night Magic Of Colombia Cruise

Barranquilla to Cartagena

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
3/31/27
From
$4,149
5-night Caribbean Cruise: Great Stirrup Cay & Dominican Republic

Roundtrip Port Canaveral

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Getaway
Departs
3/31/27
46-night 2027 World Cruise Segment: North Pacific - Singapore To Los Angeles

Singapore to Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Coral Princess
Departs
3/31/27
From
$9,189
16-night Hawaiian Islands Cruise

Roundtrip San Francisco

Cruise Line
Princess Cruises
Cruise Ship
Ruby Princess
Departs
4/1/27
From
$2,479
19-night Panama Canal & The Americas Cruise

Santiago (Valparaiso) to New York City

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
4/1/27
 
Call For Pricing
8-night Cabo Overnight, Mazatlan & Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Voyager of the Seas
Departs
4/1/27
27-night Tahiti, Hawaii & South Pacific Crossing Cruise

Auckland to Vancouver

Cruise Line
Princess Cruises
Cruise Ship
Royal Princess
Departs
4/2/27
From
$4,438
21-night Tahiti, Hawaii & South Pacific Crossing Cruise

Auckland to Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Royal Princess
Departs
4/2/27
From
$3,256
3-night Ensenada Cruise

Roundtrip Los Angeles

Cruise Line
Royal Caribbean International
Cruise Ship
Ovation of the Seas
Departs
4/2/27
7-night Wonders Of Colombia With 3-nights In Medellín, 2-nights In Cartagena Pre Cruise Cruise/Land Package

Medellin to Barranquilla

Cruise Line
AmaWaterways
Cruise Ship
AmaMelodia
Departs
4/2/27
From
$6,199
9-night Southern Caribbean & Abc Islands With History Channel Cruise

Roundtrip Ft. Lauderdale

Cruise Line
Holland America Line
Cruise Ship
Nieuw Amsterdam
Departs
4/2/27
From
$1,467
10-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/2/27
 
Call For Pricing
11-night Quito & Galapagos Outer Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/2/27
 
Call For Pricing
16-night Galapagos Outer Loop & Machu Picchu Cruise/Land Package

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
4/2/27
 
Call For Pricing
7-night East Galapagos Expedition Cruise

Baltra Island to Puerto Ayora

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
4/2/27
 
Call For Pricing
14-night East & West Galapagos Expedition Cruise

Roundtrip Baltra Island

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Mare
Departs
4/2/27
 
Call For Pricing
7-night Mexican Riviera Cruise

Roundtrip Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Discovery Princess
Departs
4/3/27
From
$1,029
16-night Panama Canal Cruise - Ocean To Ocean

Los Angeles to Ft. Lauderdale

Cruise Line
Princess Cruises
Cruise Ship
Island Princess
Departs
4/3/27
From
$2,309
16-night Panama Canal Cruise - Ocean To Ocean

Ft. Lauderdale to Los Angeles

Cruise Line
Princess Cruises
Cruise Ship
Star Princess
Departs
4/3/27
From
$2,658
15-night Panama Canal Cruise: Mexico & Costa Rica

San Diego to Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Star
Departs
4/3/27
From
$2,128
7-night Caribbean Cruise: Harvest Caye, Cozumel & Roatan

Roundtrip Galveston

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Viva
Departs
4/3/27
 
Call For Pricing
14-night Panama Canal Cruise

Ft. Lauderdale to San Diego

Cruise Line
Holland America Line
Cruise Ship
Eurodam
Departs
4/3/27
From
$3,554
20-night Panama Canal Cruise

Ft. Lauderdale to Vancouver

Cruise Line
Holland America Line
Cruise Ship
Eurodam
Departs
4/3/27
From
$4,564
10-night In Steinbeck's Wake: An Epic Voyage Through the Sea of Cortez Cruise

Roundtrip San Jose del Cabo

Cruise Line
UnCruise Adventures
Cruise Ship
Safari Voyager
Departs
4/3/27
 
Call For Pricing