Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

4,910 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

7-night Amazon Expedition Cruise - Roundtrip Nauta

Roundtrip Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
6/8/24
 
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7-night Galapagos Northern Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xpedition
Departs
6/8/24
From
$6,419
7-night Galapagos Southern Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
6/8/24
From
$6,499
7-night Galápagos Islands Cruise

Roundtrip Isla San Cristobal (Puerto Baquerizo Moreno)

Cruise Line
Silversea Cruises
Cruise Ship
Silver Origin
Departs
6/8/24
 
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7-night Eastern Caribbean: Great Stirrup Cay & Dominican Republic Cruise

Roundtrip Port Canaveral

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Jade
Departs
6/8/24
From
$1,149
16-night Panama Canal Cruise

Miami to San Diego

Cruise Line
Crystal Cruises
Cruise Ship
Crystal Serenity
Departs
6/8/24
From
$8,500
9-night Galápagos Islands – Iconic Wildlife and Sublime Scenery Plus Machu Picchu Cruise/Land Package

Lima to Quito

Cruise Line
Hurtigruten
Cruise Ship
MS Santa Cruz
Departs
6/8/24
From
$8,360
31-night Caribbean to Alaska Cruise

Miami to Vancouver

Cruise Line
Crystal Cruises
Cruise Ship
Crystal Serenity
Departs
6/8/24
From
$14,500
7-night Eastern Caribbean: Great Stirrup Cay & Dominican Republic Cruise

Roundtrip Miami

Cruise Line
Norwegian Cruise Line
Cruise Ship
Norwegian Breakaway
Departs
6/9/24
From
$1,398
7-night Galapagos Inner Loop Cruise

Roundtrip Isla Baltra

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Flora
Departs
6/9/24
From
$6,639
10-night From the Inca Empire to the Peruvian Amazon Cruise/Land Package

Roundtrip Lima

Cruise Line
Avalon Waterways
Cruise Ship
Delfin III
Departs
6/9/24
From
$5,980
17-night From the Inca Empire to the Peruvian Amazon with Galápagos Cruise Cruise/Land Package

Lima to Quito

Cruise Line
Avalon Waterways
Cruise Ship
Delfin III
Departs
6/9/24
 
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4-night Amazon Explorer Cruise

Iquitos to Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aria Amazon
Departs
6/10/24
 
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4-night Amazon Explorer Cruise - Roundtrip Nauta

Roundtrip Nauta

Cruise Line
Aqua Expeditions
Cruise Ship
Aqua Nera
Departs
6/11/24
 
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7-night Galápagos – Wildlife Wonderland Cruise/Land Package

Quito to Guayaquil

Cruise Line
Tauck Cruises
Cruise Ship
Santa Cruz II
Departs
6/11/24
From
$7,990
6-night Galápagos Islands Expedition Cruise – Iconic Wildlife and Sublime Scenery

Roundtrip Quito

Cruise Line
Hurtigruten
Cruise Ship
MS Santa Cruz
Departs
6/11/24
From
$5,311
10-night Galápagos Islands – Nine of the Best Isles Cruise/Land Package

Roundtrip Quito

Cruise Line
Hurtigruten
Cruise Ship
MS Santa Cruz
Departs
6/11/24
From
$8,097
6-night Wild Galapagos Escape Cruise

Roundtrip Guayaquil

Cruise Line
Lindblad Expeditions
Cruise Ship
National Geographic Islander II
Departs
6/11/24
From
$9,246
16-night Galapagos Southern Loop & Machu Picchu Cruise/Land Package

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xpedition
Departs
6/13/24
 
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10-night Quito & Galapagos Southern Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xpedition
Departs
6/13/24
From
$8,499
11-night Quito & Galapagos Southern Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xpedition
Departs
6/13/24
From
$8,579
16-night Galápagos Northern Loop and Machu Picchu Cruise/Land Package

Quito to Lima

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
6/13/24
 
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10-night Quito and Galápagos Northern Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
6/13/24
From
$9,099
11-night Quito and Galápagos Northern Loop Cruise/Land Package

Roundtrip Quito

Cruise Line
Celebrity Cruises
Cruise Ship
Celebrity Xploration
Departs
6/13/24
From
$9,179