Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
4,942 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
---|---|---|---|---|
13-night South American Explorer – Ocean Cruise and Mountain Views Expedition
Lima to Santiago (Valparaiso) |
Cruise Line
Hurtigruten
|
Cruise Ship
MS Roald Amundsen
|
Departs
10/8/24
|
From
$7,436
|
30-night Ultimate Adventure to Machu Picchu, Patagonia, and Antarctica Expedition
Lima to Valparaiso |
Cruise Line
Hurtigruten
|
Cruise Ship
MS Roald Amundsen
|
Departs
10/8/24
|
From
$16,610
|
7-night Ecuador and Its Galápagos Islands Cruise/Land Package
Roundtrip Quito |
Cruise Line
Avalon Waterways
|
Cruise Ship
Treasure of Galápagos
|
Departs
10/9/24
|
From
$6,003
|
11-night Ecuador and Its Galápagos Islands with the Amazon Cruise/Land Package
Roundtrip Quito |
Cruise Line
Avalon Waterways
|
Cruise Ship
Treasure of Galápagos
|
Departs
10/9/24
|
From
$8,240
|
8-night Galápagos Islands Expedition Cruise – In Darwin's Footsteps
Roundtrip Quito |
Cruise Line
Hurtigruten
|
Cruise Ship
MS Santa Cruz
|
Departs
10/9/24
|
From
$6,539
|
16-night Galapagos Northern Loop & Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
10/10/24
|
From
$13,319
|
10-night Quito & Galapagos Northern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
10/10/24
|
From
$8,319
|
11-nght Quito & Galapagos Northern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xpedition
|
Departs
10/10/24
|
From
$8,399
|
16-night Galápagos Southern Loop and Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
10/10/24
|
From
$12,899
|
10-night Quito and Galápagos Southern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
10/10/24
|
From
$7,899
|
11-night Quito and Galápagos Southern Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Xploration
|
Departs
10/10/24
|
From
$7,979
|
17-night Panama Canal and the Pacific Coast Cruise
Ft. Lauderdale to Los Angeles |
Cruise Line
Viking Cruises
|
Cruise Ship
Viking Neptune
|
Departs
10/10/24
|
From
$6,299
|
7-night Wild Galapagos Escape Cruise
Roundtrip Guayaquil |
Cruise Line
Lindblad Expeditions
|
Cruise Ship
National Geographic Islander II
|
Departs
10/10/24
|
Call For Pricing
|
16-night Panama Canal Cruise
San Diego to Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Eurodam
|
Departs
10/10/24
|
From
$2,159
|
7-night West Galapagos Cruise - Puerto Ayora to Isla Baltra
Puerto Ayora to Isla Baltra |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
10/11/24
|
Call For Pricing
|
14-night West & East Galapagos Cruise - Roundtrip Santa Cruz Island
Puerto Ayora to Isla Baltra |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aqua Mare
|
Departs
10/11/24
|
Call For Pricing
|
10-night Quito & Galapagos Inner Loop Cruise/Land Package
Roundtrip Quito |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
10/11/24
|
From
$11,199
|
16-night Galapagos Inner Loop & Machu Picchu Cruise/Land Package
Quito to Lima |
Cruise Line
Celebrity Cruises
|
Cruise Ship
Celebrity Flora
|
Departs
10/11/24
|
From
$17,879
|
7-night Amazon Expedition Cruise
Iquitos to Nauta |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aria Amazon
|
Departs
10/11/24
|
Call For Pricing
|
3-night Amazon Discovery Cruise
Iquitos to Nauta |
Cruise Line
Aqua Expeditions
|
Cruise Ship
Aria Amazon
|
Departs
10/11/24
|
Call For Pricing
|
14-night Peru and the Galápagos Islands Cruise/Land Package
Lima to Guayaquil |
Cruise Line
Tauck Cruises
|
Cruise Ship
Isabela II
|
Departs
10/11/24
|
From
$13,590
|
19-night From the Inca Empire to the Peruvian Amazon with the Nazca Lines and Galápagos Cruise Cruise/Land Package
Lima to Quito |
Cruise Line
Avalon Waterways
|
Cruise Ship
Delfin III
|
Departs
10/11/24
|
Call For Pricing
|
3-night Ensenada Cruise
Roundtrip Los Angeles |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Navigator of the Seas
|
Departs
10/11/24
|
From
$278
|
9-night Western Caribbean Cruise
Roundtrip Tampa |
Cruise Line
Royal Caribbean International
|
Cruise Ship
Serenade of the Seas
|
Departs
10/11/24
|
From
$638
|