Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.
Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.
There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.
4,912 cruises cruises
Includes free extras and bonus savings available only from CruiseInsider.
Itinerary | Cruise Line | Cruise Ship | Departing | From Price |
---|---|---|---|---|
21-night Eastern & Southern Caribbean: Leeward & Abc Islands Cruise
Roundtrip Miami |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
3/14/26
|
From
$3,454
|
10-night Southern Caribbean: Amber Cove & Abc Islands Cruise
Roundtrip Miami |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
3/25/26
|
From
$1,106
|
17-night Southern & Eastern Caribbean: Abc Islands & Bahamas Cruise
Roundtrip Miami |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
3/25/26
|
From
$2,934
|
7-night Eastern Caribbean: Amber Cove & Bahamas Cruise
Roundtrip Miami |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
4/4/26
|
From
$1,299
|
14-night Eastern Caribbean: Bahamas & San Juan Cruise
Roundtrip Miami |
Cruise Line
Holland America Line
|
Cruise Ship
Zuiderdam
|
Departs
4/4/26
|
From
$1,592
|
56-night Tales Of The South Pacific Cruise
Vancouver to San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
9/25/24
|
Call For Pricing
|
51-night Tales Of The South Pacific Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
9/30/24
|
From
$6,999
|
17-night Circle Hawaii Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
11/20/24
|
From
$1,493
|
28-night Circle Hawaii & Mexican Riviera/Sea Of Cortez Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
11/20/24
|
From
$3,999
|
11-night Mexican Riviera & Sea Of Cortez Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
12/7/24
|
From
$1,007
|
27-night Mexican Riviera/Sea Of Cortez & Circle Hawaii Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
12/7/24
|
From
$2,924
|
16-night Circle Hawaii Holiday Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
12/18/24
|
From
$2,659
|
31-night Circle Hawaii & Panama Canal Holiday Cruise
San Diego to Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
12/18/24
|
From
$4,934
|
15-night Panama Canal Cruise
San Diego to Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
1/3/25
|
From
$1,862
|
27-night Amazon Explorer Cruise
Roundtrip Ft. Lauderdale |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
2/8/25
|
From
$6,599
|
15-night Panama Canal Cruise
Ft. Lauderdale to San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
3/7/25
|
From
$2,299
|
11-night Mexican Riviera & Sea Of Cortez Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
3/22/25
|
From
$1,659
|
10-night Mexican Riviera & Sea Of Cortez Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/2/25
|
From
$1,007
|
7-night Baja Peninsula & Sea Of Cortez Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/12/25
|
From
$1,019
|
14-night Baja Peninsula & Classic California Coast Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/12/25
|
From
$1,919
|
7-night Classic California Coast Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/19/25
|
From
$746
|
14-night Mexican Riviera & Classic California Coast Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/19/25
|
From
$1,919
|
7-night Mexican Riviera Cruise
Roundtrip San Diego |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/26/25
|
From
$746
|
11-night Mexican Riviera & Pacific Coast Cruise
San Diego to Vancouver, BC |
Cruise Line
Holland America Line
|
Cruise Ship
Zaandam
|
Departs
4/26/25
|
From
$1,459
|