Central & South America

Destinations / Central & South America

Whether you’re an archaeology buff, outdoor adventurer or action-seeker, Central and South America won’t disappoint. With so many diverse travel options and unique destinations to see, an adventure to Central and South America means you’ll be surrounded by warm people, wondrous nature and wild adventure throughout your journey.

Visit the ancient Inca capital of Cuzco. Zipline through the jungles of Costa Rica. Explore the lost city of Machu Picchu. Relax on the warm beaches of Mexico. Immerse yourself in the rich culture of Brazil. Experience the biodiversity of the Amazon rainforest. There are miles of beautiful beaches, endless rivers, metropolitan cities, unexplored rainforest and countless mythical and memorable sites scattered throughout the continent. And you can see it all while being pampered every stop along the way on a luxury cruise.

There are dozens of cruise options to Central and South America, so speak to a CruiseInsider today at 1 (877) 734-6858 to start planning your own unique experience or choose from one of the many voyages offered below.

Central & South America Cruises

4,914 cruises cruises

Includes free extras and bonus savings available only from CruiseInsider.

86-night From The Arctic To Antarctica Cruise

Nuuk to Ushuaia

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
9/3/25
From
$74,995
86-night From The Arctic To Antarctica Cruise

Nuuk to Ushuaia

Cruise Line
Viking Cruises
Cruise Ship
Viking Polaris
Departs
9/17/26
From
$75,995
85-night South America Discovery From Hamburg Cruise

Roundtrip Hamburg

Cruise Line
Cunard Line
Cruise Ship
Queen Victoria
Departs
1/4/25
 
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81-night San Francisco To Southampton Cruise

San Francisco to London (Southampton)

Cruise Line
Cunard Line
Cruise Ship
Queen Anne
Departs
2/4/25
From
$11,199
79-night Ultimate Pacific Traveler Voyage

Los Angeles to Sydney

Cruise Line
Oceania Cruises
Cruise Ship
Regatta
Departs
10/3/24
From
$19,799
79-night Australia, Asia & Alaska Cruise

Vancouver to Sydney

Cruise Line
Viking Cruises
Cruise Ship
Viking Orion (Ocean)
Departs
9/14/25
 
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79-night Circle South America Grand Voyage

Roundtrip Miami

Cruise Line
Azamara
Cruise Ship
Azamara Quest
Departs
1/6/26
From
$18,389
78-night Australia, Asia, and Alaska Cruise

Vancouver to Sydney

Cruise Line
Viking Cruises
Cruise Ship
Viking Orion (Ocean)
Departs
9/11/24
 
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78-night South America Discovery Cruise

Roundtrip London (Southampton)

Cruise Line
Cunard Line
Cruise Ship
Queen Victoria
Departs
1/9/25
 
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78-night Australia, Asia, and Alaska Cruise

Sydney to Vancouver

Cruise Line
Viking Cruises
Cruise Ship
Viking Orion (Ocean)
Departs
3/21/25
 
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77-night Tale of Three Continents - 2025 World Cruise Segment

Miami to Singapore

Cruise Line
Oceania Cruises
Cruise Ship
Insignia
Departs
1/5/25
 
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77-night Spanning The Americas Voyage - 2026 World Cruise Segment

Los Angeles to San Diego

Cruise Line
Oceania Cruises
Cruise Ship
Vista
Departs
12/20/25
From
$28,749
77-night Australia, Asia & Alaska Cruise

Sydney to Vancouver

Cruise Line
Viking Cruises
Cruise Ship
Viking Orion (Ocean)
Departs
3/30/26
From
$35,995
75-night Grand South Pacific Expedition Cruise

Perth (Fremantle) to Santiago (Valparaiso)

Cruise Line
Silversea Cruises
Cruise Ship
Silver Cloud Expedition
Departs
8/25/24
 
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74-night Grand South Pacific Expedition Cruise

Perth (Fremantle) to Santiago (Valparaiso)

Cruise Line
Silversea Cruises
Cruise Ship
Silver Cloud Expedition
Departs
8/25/24
 
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74-night Australia to South America Cruise

Perth (Fremantle) to Santiago (Valparaiso)

Cruise Line
Silversea Cruises
Cruise Ship
Silver Cloud Expedition
Departs
8/20/25
 
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74-night Southern Seas Saga Voyage

Los Angeles to Hong Kong

Cruise Line
Oceania Cruises
Cruise Ship
Regatta
Departs
11/26/25
From
$22,199
71-night Grand South America Voyage

Roundtrip Ft. Lauderdale

Cruise Line
Silversea Cruises
Cruise Ship
Silver Ray
Departs
1/20/25
 
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70-night Longitudinal World Cruise II

Duluth to Ushuaia

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
9/26/24
 
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68-night Longitudinal World Cruise V

Buenos Aires to Milwaukee

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
2/20/25
From
$57,495
68-night Kimberley Expedition & Remote Islands Of The Pacific Cruise

Broome to Santiago (San Antonio)

Cruise Line
Seabourn
Cruise Ship
Seabourn Pursuit
Departs
8/24/25
From
$42,994
68-night Longitudinal World Cruise VI

Buenos Aires to Milwaukee

Cruise Line
Viking Cruises
Cruise Ship
Viking Octantis
Departs
2/24/26
From
$52,995
66-night World Cruise Segment - Panama Canal, South Pacific & Indian Ocean Cruise

Ft. Lauderdale to Dubai

Cruise Line
Princess Cruises
Cruise Ship
Island Princess
Departs
1/5/25
 
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65-night Grand Pacific Hemispheres Voyage

Los Angeles to Auckland

Cruise Line
Oceania Cruises
Cruise Ship
Regatta
Departs
10/3/24
 
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